Effect of residual doxycycline concentrations on resistance selection and transfer in porcine commensal escherichia coli.

Last updated on 1-10-2018 by Thibault Degiuli

Peer reviewed scientific article

SCIENSANO

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Résumé:

Pig feed may contain various levels of antimicrobial residues due to cross-contamination. A previous study showed that a 3% carry-over level of doxycycline (DOX) in the feed results in porcine faecal concentrations of approximately 4 mg/L. This study aimed to determine the effect of residual DOX concentrations (1 and 4 mg/L) in vitro on selection of DOX resistant porcine commensal E. coli and transfer of their resistance plasmids. Three different DOX resistant porcine commensal E. coli strains and their plasmids were characterized. These strains were each brought in competition with a susce…

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