TY - JOUR T1 - Enantiomeric fraction of hexabromocyclododecanes in foodstuff from the Belgian market JF - Chemosphere Y1 - 2020 A1 - Ronan Cariou A1 - Svetlana V. Malysheva A1 - Séverine Goscinny A1 - Bruno Le Bizec A1 - Joris Van Loco A1 - Gaud Dervilly KW - Chiral compound KW - Enantiomer KW - Environmental contaminant KW - food KW - HBCDD AB -

Diet is considered a major route of human exposure to hexabromocyclododecane, a chiral environmental contaminant. A previous study reported on the occurrence of hexabromocyclododecane diastereoisomers in food items of animal origin collected in Belgium. The present study reports further results on corresponding enantiomeric fractions of the same samples. None of the samples could be considered as racemic for the α-isomer suggesting that foodstuff contamination occurred prior to death of the corresponding producing animal and was not the result of the food item being in contact with technical HBCDD. Non-racemic chiral signatures were also observed for β- and γ-isomers. We conclude that, depending on their dietary habits, different individuals might be overall exposed to non-racemic profiles. Considering that toxicological effects are enantiomer-dependent, this could modulate potential adverse effects.

VL - 260 M3 - 10.1016/j.chemosphere.2020.127607 ER -