TY - JOUR T1 - Analytical characterization of "etonitazepyne," a new pyrrolidinyl-containing 2-benzylbenzimidazole opioid sold online. JF - Drug Test Anal Y1 - 2021 A1 - Peter Blanckaert A1 - Margot Balcaen A1 - Celine Vanhee A1 - Martijn Risseeuw A1 - Michael Canfyn A1 - Bart Desmedt A1 - Van Calenbergh, Serge A1 - Eric Deconinck KW - Benzimidazoles KW - etonitazene KW - new psychoactive substances KW - opioid NPS KW - pyrrolidine analogue AB -

This paper reports on the identification and full chemical characterization of the substance colloquially called "etonitazepyne" or "N-pyrrolidino etonitazene" (2-(4-ethoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzo[d]imidazole), a potent NPS opioid of the 5-nitrobenzimidazole class. Identification of etonitazepyne was performed, on a sample purchased during routine monitoring of the drug market, using GC-MS, HRAM LC-MS/MS, H NMR, and FTIR. The chromatographic data, together with the FTIR data, indicated the presence of a highly pure compound and already indicated a benzimidazole structure. The specific benzimidazole regio-isomer was confirmed using H NMR spectroscopy, resulting in the unambiguous identification of etonitazepyne.

VL - 13 CP - 9 M3 - 10.1002/dta.3113 ER -