<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dendooven, Tom</style></author><author><style face="normal" font="default" size="100%">Van den Bossche, An</style></author><author><style face="normal" font="default" size="100%">Hendrix, Hanne</style></author><author><style face="normal" font="default" size="100%">Pieter-Jan Ceyssens</style></author><author><style face="normal" font="default" size="100%">Voet, Marleen</style></author><author><style face="normal" font="default" size="100%">Bandyra, K J</style></author><author><style face="normal" font="default" size="100%">De Maeyer, Marc</style></author><author><style face="normal" font="default" size="100%">Aertsen, Abram</style></author><author><style face="normal" font="default" size="100%">Noben, Jean-Paul</style></author><author><style face="normal" font="default" size="100%">Hardwick, Steven W</style></author><author><style face="normal" font="default" size="100%">Luisi, Ben F</style></author><author><style face="normal" font="default" size="100%">Lavigne, Rob</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Viral interference of the bacterial RNA metabolism machinery.</style></title><secondary-title><style face="normal" font="default" size="100%">RNA Biol</style></secondary-title><alt-title><style face="normal" font="default" size="100%">RNA Biol</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">bacteria</style></keyword><keyword><style  face="normal" font="default" size="100%">Bacteriophages</style></keyword><keyword><style  face="normal" font="default" size="100%">Endoribonucleases</style></keyword><keyword><style  face="normal" font="default" size="100%">Host-Pathogen Interactions</style></keyword><keyword><style  face="normal" font="default" size="100%">Multienzyme Complexes</style></keyword><keyword><style  face="normal" font="default" size="100%">Polyribonucleotide Nucleotidyltransferase</style></keyword><keyword><style  face="normal" font="default" size="100%">Protein Binding</style></keyword><keyword><style  face="normal" font="default" size="100%">Pseudomonas aeruginosa</style></keyword><keyword><style  face="normal" font="default" size="100%">RNA Helicases</style></keyword><keyword><style  face="normal" font="default" size="100%">RNA Stability</style></keyword><keyword><style  face="normal" font="default" size="100%">RNA, Bacterial</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2017 Jan 02</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">10</style></number><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">6-10</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;In a recent publication, we reported a unique interaction between a protein encoded by the giant myovirus phiKZ and the Pseudomonas aeruginosa RNA degradosome. Crystallography, site-directed mutagenesis and interactomics approaches revealed this 'degradosome interacting protein' or Dip, to adopt an 'open-claw' dimeric structure that presents acidic patches on its outer surface which hijack 2 conserved RNA binding sites on the scaffold domain of the RNase E component of the RNA degradosome. This interaction prevents substrate RNAs from being bound and degraded by the RNA degradosome during the virus infection cycle. In this commentary, we provide a perspective into the biological role of Dip, its structural analysis and its mysterious evolutionary origin, and we suggest some therapeutic and biotechnological applications of this distinctive viral protein.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><custom1><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/27834591?dopt=Abstract</style></custom1><section><style face="normal" font="default" size="100%">6</style></section></record></records></xml>