<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dominique Van Beckhoven</style></author><author><style face="normal" font="default" size="100%">Florence, E</style></author><author><style face="normal" font="default" size="100%">De Wit, S</style></author><author><style face="normal" font="default" size="100%">Chloé Wyndham-Thomas</style></author><author><style face="normal" font="default" size="100%">A Sasse</style></author><author><style face="normal" font="default" size="100%">Herman Van Oyen</style></author><author><style face="normal" font="default" size="100%">J Macq</style></author></authors><translated-authors><author><style face="normal" font="default" size="100%">the Belgian Research on AIDS, HIV Consortium (BREACH)</style></author></translated-authors></contributors><titles><title><style face="normal" font="default" size="100%">Incidence rate, predictors and outcomes of interruption of HIV care: nationwide results from the Belgian HIV cohort</style></title><secondary-title><style face="normal" font="default" size="100%">HIV Medicine</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">AIDS</style></keyword><keyword><style  face="normal" font="default" size="100%">HIV</style></keyword><keyword><style  face="normal" font="default" size="100%">HIV care</style></keyword><keyword><style  face="normal" font="default" size="100%">loss to follow-up</style></keyword><keyword><style  face="normal" font="default" size="100%">maintenance</style></keyword><keyword><style  face="normal" font="default" size="100%">re-engagement</style></keyword><keyword><style  face="normal" font="default" size="100%">retention</style></keyword><keyword><style  face="normal" font="default" size="100%">SIDA</style></keyword><keyword><style  face="normal" font="default" size="100%">VIH</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jan-10-2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">21</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Objectives&lt;/p&gt;

&lt;p&gt;We aimed to study the incidence rate, predictors and outcomes of HIV care interruption (HCI) in&lt;/p&gt;

&lt;p&gt;Belgium.&lt;/p&gt;

&lt;p&gt;Methods&lt;/p&gt;

&lt;p&gt;We analysed data for adult patients with at least two HIV care records in the Belgian HIV cohort&lt;/p&gt;

&lt;p&gt;between 1 January 2007 and 31 December 2016. An HCI episode was defined as 1 year without an&lt;/p&gt;

&lt;p&gt;HIV care record. The HCI incidence rate was analysed using Poisson regression, return to HIV care&lt;/p&gt;

&lt;p&gt;using a cumulative incidence function with death as a competing risk, and viral load (VL) status&lt;/p&gt;

&lt;p&gt;upon return to HIV care using logistic regression.&lt;/p&gt;

&lt;p&gt;Results&lt;/p&gt;

&lt;p&gt;We included 16 066 patients accounting for 78 625 person-years of follow-up. The incidence rate&lt;/p&gt;

&lt;p&gt;of HCI was 5.3/100 person-years [95% confidence interval (CI) 5.1 5.4/100 person-years]. The –&lt;/p&gt;

&lt;p&gt;incidence of return to HIV care after HCI was estimated at 77.5% (95% CI 75.7 79.2%). Of those –&lt;/p&gt;

&lt;p&gt;who returned to care, 43.7% had a VL ≤ 200 HIV-1 RNA copies/mL, suggesting care abroad or&lt;/p&gt;

&lt;p&gt;suboptimal care (without an HIV-related care record) in Belgium during the HCI, and 56.3%&lt;/p&gt;

&lt;p&gt;returned without controlled VL and were therefore considered as having experienced a real gap in&lt;/p&gt;

&lt;p&gt;HIV care; they represented 2.3/100 person-years of follow-up. Factors individually associated with&lt;/p&gt;

&lt;p&gt;HCI were no antiretroviral therapy (ART) uptake, lower age, injecting drug use, non-Belgian&lt;/p&gt;

&lt;p&gt;nationality, male gender, not being a man who has sex with men, a shorter time since HIV&lt;/p&gt;

&lt;p&gt;diagnosis, no high blood pressure and CD4 count &amp;lt; 350 cells/μL.&lt;/p&gt;

&lt;p&gt;Conclusions&lt;/p&gt;

&lt;p&gt;This study highlights the need to investigate return to care and viral status at return, to better&lt;/p&gt;

&lt;p&gt;understand HCI. Identified predictors can help health care workers to target patients at higher risk&lt;/p&gt;

&lt;p&gt;of HCI for awareness and support.&lt;/p&gt;
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