<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>32</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lise De Barsy</style></author><author><style face="normal" font="default" size="100%">Charlotte De Bleye</style></author><author><style face="normal" font="default" size="100%">P.Y. Sacré</style></author><author><style face="normal" font="default" size="100%">Sophia Barhdadi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development of vibrational spectroscopic methods combined with chemometrics for the detection and quantification of nicotine in e-liquids.</style></title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chemometrics</style></keyword><keyword><style  face="normal" font="default" size="100%">e-cigarettes</style></keyword><keyword><style  face="normal" font="default" size="100%">infra-red spectroscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">Nicotine</style></keyword><keyword><style  face="normal" font="default" size="100%">RAMAN</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2021</style></date></pub-dates></dates><publisher><style face="normal" font="default" size="100%">ULg</style></publisher><pub-location><style face="normal" font="default" size="100%">Liège, Belgium</style></pub-location><pages><style face="normal" font="default" size="100%">54</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;E-cigarette have become a popular alternative to smoking tobacco cigarettes. They are sold in vapeshops and online. However, in Belgium, it is prohibited to import or to buy nicotine-containing e-liquids via the internet. The ban on long-distance sale implies that postal packages containing e-liquids are checked at customs. Furthermore, there is a demand of vapeshop-inspectors for on-site screening of e-liquid samples to check their compliance to the TPD i.e. non-nicotine labeled e-liquids should not contain nicotine and the maximum nicotine concentration of nicotine-labeled e-liquids should be respected (&amp;lt; 20mg/ml). The main objective of this paper is to develop a handheld NIR, Raman or SERS spectroscopic method combined with chemometrics (PLS and PCA) for detection and quantification of nicotine in e-liquids out of the laboratory. Raman and SERS, combined with chemometrics were proved to be promising tools for the detection and quantification of nicotine in e-liquids. However, improvement of Raman PLS model and further SERS studies with tests on a larger number of samples are still needed.&lt;/p&gt;
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