Foot-and-mouth disease vaccine potency testing in cattle using homologous and heterologous challenge strains: precision of the "Protection against Podal Generalisation" test.

Last updated on 22-8-2019 by Anonymous (non vérifié)

Peer reviewed scientific article



The level of protection conferred by foot-and-mouth disease (FMD) vaccines in primovaccinated animals primarily depends on the potency of the vaccine and the relatedness of the vaccine strain and circulating field isolate. The “Gold Standard” FMD vaccine potency test is the in vivo test performed in the target species. The objective of the study was to determine the precision of the in vivo “Protection against Podal Generalisation” (PPG) FMD vaccine potency test in cattle using homologous (vaccine quality control) and heterologous (vaccine matching) viral challenge. The overall level of pro…

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