Resistance mechanism against fluoroquinolones in Mycoplasma hyopneumoniae field isolates.

Last updated on 23-8-2019 by Anonymous (non vérifié)

Peer reviewed scientific article



The quinolone resistance-determining regions (QRDR) of gyrA, gyrB, parC, and parE of ten Mycoplasma hyopneumoniae field isolates that were either sensitive (5) or resistant (5) to the fluoroquinolones flumequine and enrofloxacin were characterized. In all five resistant isolates, one point mutation (C -→ A) in parC was found, resulting in an amino acid change from serine to tyrosine at position 80 (Escherichia coli numbering). For four of these isolates, this was the only mutation found. These isolates had a minimum inhibitory concentration (MIC) of enrofloxacin of 0.5 microg/ml, whereas f…

Associated health topics:

QR code

QR code for this page URL