Last updated on 14-12-2020 by Jill Alexandre
Auteurs
EFSA Panel on Contaminants in the Food Chain (CONTAM),; Schrenk, Dieter; Bignami, Margherita; Bodin, Laurent; Chipman, James; del Mazo, Jesús; Grasl‐Kraupp, Bettina; Hogstrand, Christer; Hoogenboom, Laurentius; Leblanc, Jean‐Charles; Nebbia, Carlo; Ntzani, Evangelia; Petersen, Annette; Sand, Salomon; Schwerdtle, Tanja; Vleminckx, Christiane; Wallace, Heather; Guérin, Thierry; Massanyi, Peter; van Loveren, Henk; Baert, Katleen; Gergelova, Petra; Nielsen, ElsaMots-clés
Résumé:
The European Commission asked EFSA to update its previous Opinion on nickel in food and drinking water, taking into account new occurrence data, the updated benchmark dose (BMD) Guidance and newly available scientific information. More than 47,000 analytical results on the occurrence of nickel were used for calculating chronic and acute dietary exposure. An increased incidence of post‐implantation loss in rats was identified as the critical effect for the risk characterisation of chronic oral exposure and a BMDL10 of 1.3 mg Ni/kg body weight (bw) per day was selected as the refere…