Vouliez-vous dire
agonist

Résultats de la recherche - 38 results

Optimization of Long-Acting Bronchodilator Dose Ratios Using Isolated Guinea Pig Tracheal Rings for Synergistic Combination Therapy in Asthma and COPD.

Volume 15, Issue 8 (2022) Abstract: The co-administration of a long-acting β2-agonist (LABA), and a long-acting muscarinic antagonist (LAMA), has been shown to be beneficial in the management of ...

Insights From Early Clinical Trials Assessing Response to mRNA SARS-CoV-2 Vaccination in Immunocompromised Patients.

antimetabolites, CTLA4 agonists or JAK inhibitors, and vaccination with BNT162 b2 versus mRNA1273 vaccine. Finally, we review the first data on third dose mRNA vaccine administration in immunocompromised patients ...

Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation through a TLR2/MyD88 Pathway.

a nonpathogenic mold. A lack of TLR2 signaling recapitulated the exacerbation of the Th2 response observed in the absence of MyD88 signaling, whereas TLR2 agonist dampened the response induced with and conidia. ...

Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays

agonistic and antagonistic endocrine activity of 9 environmentally relevant PAH s using three different CALUX bioassays: The AhR- CALUX, The ER α- CALUX and PPAR γ- CALUX. For the PPAR γ- CALUX anthracene, ...

Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays

pyrene and fluorene showed a weak agonistic activity for the PPAR y receptor. Only BaP showed a weak antagonistic activity. In both the agonistic and antagonistic tests, no effects were observed in ...

PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.

nature of the calcium signals and the response regulation upon repeated exposures of astrocytes to the agonist (S)-3,5-dihydroxyphenylglycine. We show that upon repeated mGluR5 activations, a robust ...

Modulation de l’activité transcriptionelle de récepteurs nucléaires par les produits de migration de matériaux en plastique destinés aux jeunes enfants

activité sur aucun des récepteurs. La plupart des activités agonistes et antagonistes ont été observées respectivement sur le récepteur ER (29 substances sur 35) et PPAR y (20 substances sur 35). Aucune ...

Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays.

1mM. Only twelve chemicals did not show any activity towards any of the nuclear receptors, while fifty three compounds showed a possible endocrine activity. Most of the agonistic activities were observed ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

innate responses and contributing to the development of specific adaptive immune responses. Novel adjuvants have been developed based on agonists of PRR s. Areas covered: Lipid pathogen-associated ...

In vitro endocrine activity of mycotoxins and their mixtures.

animals by influencing the synthesis, metabolism or transport of hormones; or by interacting directly with the hormone receptor (as an agonist or antagonist). Over the past decades there has been a growing ...

QR code

QR code for this page URL