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STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With.

associated Th2 cytokines during infection in the BALB /c model. In the absence of STAT6 and IL-12p40 signaling, double knockout (DKO) susceptible BALB /c mice displayed reduced footpad swelling and ulcerative ...

Study of the virulence of serotypes 4 and 9 of African horse sickness virus in IFNAR(-/-), Balb/C and 129 Sv/Ev mice.

Interferon-alpha mice Mice, Inbred BALB C Mice, Knockout Receptor, Interferon alpha-beta RNA, Double-Stranded Serogroup virulence Abstract: African horse sickness virus (AHSV) is a double-stranded RNA virus which ...

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK651

Mice,Knockout ON oncology pathology pharmacology physiology protein Protein Kinases regulation Research Research Support response result results Role SB- IM stress survival Target Tissue TOR Serine-Threonine ...

Mice genetically inactivated in interleukin-17A receptor are defective in long-term control of Mycobacterium tuberculosis infection.

Number 231, p.220-31 (2013) Keywords: Animals Cytokines Enzyme-Linked Immunosorbent Assay Flow Cytometry mice Mice, Inbred C57BL Mice, Knockout Mycobacterium tuberculosis Receptors, Interleukin-17 ...

Induction of the specific allergic immune response is independent of proteases from the fungus Alternaria alternata.

for the polyclonal IgE response. Th2 responses and lung inflammation were readily induced in TLR4 knockout mice. In contrast, lung inflammation, Th2 responses, cytokine productions, and antibody ...

Biochemical and immunological characterization of a cpn60.1 knockout mutant of Mycobacterium bovis BCG1265

culture data differences electronic function gene growth health inactivation Increase Increases Institute IS IT journal Less Lung M MEDIA mice Mycobacterium Mycobacterium bovis Mycobacterium tuberculosis ON ...

Effect of PstS sub-units or PknD deficiency on the survival of Mycobacterium tuberculosis.

Tuberculosis (Edinb), Volume 90, Issue 6, p.338-45 (2010) Keywords: Animals ATP-Binding Cassette Transporters Bacterial Proteins Blotting, Western Cell Proliferation Gene Expression Regulation, Bacterial mice ...

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice.

Kris Source: J Clin Invest, Volume 119, Issue 6, p.1626-37 (2009) Keywords: Animals Disease Models, Animal DNA-Binding Proteins Immunity, Innate Kinetics Liver X Receptors mice Mice, Inbred C57BL Mice ...

Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.

mice Mice, Inbred C57BL Mice, Knockout T-Lymphocytes, Cytotoxic Tuberculosis Vaccines Vaccination Vaccines, DNA Abstract: Reactivation tuberculosis (TB) is a serious problem in immunocompromised ...

CD4+ T cells contain Mycobacterium tuberculosis infection in the absence of CD8+ T cells in mice vaccinated with DNA encoding Ag85A.

tuberculosis challenge infection. In addition, Ag85A DNA-vaccinated IFN-gamma gene knockout mice produced Ag85-specific antibodies and IL-2 but died rapidly following a M. tuberculosis challenge infection. ...

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