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Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells

were developed based on an extended reference dataset of 38 chemicals including existing as well as newly generated gene expression data. Both unsupervised and supervised machine learning algorithms were ...

Efficient control of Japanese encephalitis virus in the central nervous system of infected pigs occurs in the absence of a pronounced inflammatory immune response.

3 Nakayama strain. Clinical signs were assessed daily, and viral spread was followed by RT-qPCR. mRNA expression profiles were determined to study immune responses in the CNS. RESULTS: Besides a delay of ...

Clonal Spread of Candida glabrata Bloodstream Isolates and Fluconazole Resistance Affected by Prolonged Exposure: a 12-Year Single-Center Study in Belgium.

8 (2018) Keywords: antifungal resistance Candida glabrata Gene Expression genotypic identification Abstract: is a major cause of candidemia in immunocompromised patients and is characterized by a high-level ...

Early immune responses and profiling of cell-mediated immunity-associated gene expression in response to rHVT-IBD vaccination

Publication Type: Peer reviewed scientific article Authors: Ingrao, Fiona; Fabienne Rauw; Mieke Steensels; Thierry van den Berg; Bénédicte Lambrecht Source: Vaccine, Volume 36 (2018) Health Topics:  Diergezondheid Animal health Santé animale Manuscript ve ...

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.

Issue 9, p.2215-29 (2016) Keywords: Carcinogens Cell Line, Tumor Computational Biology Dose-Response Relationship, Drug Gene Expression Profiling Gene Expression Regulation Genome-Wide Association Study ...

A Versatile Panel of Reference Gene Assays for the Measurement of Chicken mRNA by Quantitative PCR.

One, Volume 11, Issue 8, p.e0160173 (2016) Keywords: Algorithms Animals Chick Embryo Chickens Gene Expression Profiling Genes Influenza A Virus, H5N1 Subtype Influenza in Birds Real-Time Polymerase Chain ...

CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells.

(-) MP s remain controversial. We show here that intestinal CD103 (-) CD11 b(+) MP s can be separated clearly into DC s and mφs based on phenotype, gene profile, and kinetics. CD64 (-) CD103 (-) CD11 ...

Molecular typing of monophasic Salmonella 4,[5]:i:- strains isolated in Belgium (2008-2011).

possessed but did not express the phase II flagellin gene (23.3%). Multiple Locus Variable Number of Tandem Repeats Analysis (MLVA) revealed many but closely related profiles in the fljB-negative S. ...

A multifaceted study of Pseudomonas aeruginosa shutdown by virulent podovirus LUZ19

Ceyssens Source: MBio., Volume 4, Issue 2, Number 13, p.e00061- 13 (2013) Keywords: Bacteriophages Gene Expression Profiling Microarray Analysis mRNA RNA-seq Abstract: In contrast to the rapidly increasing ...

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