Résultats de la recherche - 16 results
Efficient control of Japanese encephalitis virus in the central nervous system of infected pigs occurs in the absence of a pronounced inflammatory immune response.
hematogenous and neuronal pathways, but replication in the brain was mostly efficiently suppressed and associated with a type I IFN-independent activation of OAS1 expression. In the olfactory bulb and thalamus, ...
Collaborative data collection by TREAT-NMD Registries to support post-marketing surveillance in Spinal Muscular Atrophy
atrophy (SMA) is a rare genetic neuromuscular disorder characterized by a loss of motor neurons in the spinal cord and the brainstem, leading to muscle weakness and atrophy. The estimated incidence is ...
Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.
proinflammatory gene expression and infiltration and activation of immune cells in brain. Specific deletion of in T cells also delayed disease development while deletion in myeloid cells, neuronal cells or NK cells ...
Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa.
kinase, induces a dramatic cytoskeletal reorganization and BHV-1 Us9, a tail-anchored membrane protein, is required for axonal transport of viruses in neurons. In this study, we investigated the role of Us3 ...
Age-Dependent Differences in Pseudorabies Virus Neuropathogenesis and Associated Cytokine Expression.
enhanced viral replication and associated immunopathology in immature TG and the central nervous system neurons of 2-week-old pigs and that neurological disease is related with extensive viral replication ...
Complete Genome Sequence of Pseudorabies Virus Reference Strain NIA3 Using Single-Molecule Real-Time Sequencing.
3 (2016) Abstract: Pseudorabies virus (PRV) is the causative agent of Aujeszky’s disease in pigs. PRV strains are also used as model organisms for the study of alphaherpesvirus biology or for neuronal ...
Biosafety of Gene Therapy Vectors Derived From Herpes Simplex Virus Type 14581
effects environment environmental risk assessment Functional gene gene therapy gene transfer genomic Genomics Hand Human Humans interaction interactions Interference IS IT lifetime MVA neurological Neurons ...
Autophagy and phagocytosis-like cell cannibalism exert opposing effects on cellular survival during metabolic stress4383
IS IT journal Laboratories Lead Lithium Chloride means mechanism mechanisms metabolism Neurons ON Phagocytosis pharmacology PROCESSES protein Protein Kinases Proteins Receptor Regulatory Research ...
An appetite for destruction: from self-eating to cell cannibalism as a neuronal survival strategy4382
Proteins electronic enzymology feedback Functional Genetic genetics im IS journal Laboratories mechanism metabolism Neurons nutrient Photoreceptor Cells,Invertebrate prevent PROCESSES protein Protein Kinases ...
Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy4388
functions Genetic genetics Glucose Humans im IS IT journal Laboratories LEVEL levels metabolism Metformin Neurons ON Oxygen Pathways PROCESSES protein Protein Kinases Ratio Research Research Support REVIEW ...