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Résultats de la recherche - 38 results
Host transcriptome profiling for resistance against lumpy skin disease (LSD).
Dirk Jan Source: BMC Res Notes, Volume 18, Issue 1 (2025) Keywords: Animals Cattle Disease Resistance Gene Expression Profiling Gene Ontology Interleukin 1 Receptor Antagonist Protein Lumpy skin disease ...
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.
expansion of infected CD8 T cells displaying effector and exhaustion gene signatures, including GZMA, GNLY, PD-1, and TOX2 expression. Then, among viral genes expressed in infected CD8 T cells, we uncovered ...
Clinical performance of the novel full-genotyping OncoPredict HPV Quantitative Typing assay using the VALGENT framework.
multiplex real-time PCR quantitative assay targeting E6 / E7 genes, allowing individual viral load determination of 12 high-risk (HR) HPV types. Quality controls for sample adequacy, efficiency of nucleic ...
Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety
two different STEC strains, and we could cluster separately the reads corresponding to each strain and perform relatedness (phylogeny), however not all genes harbored in the isolate’s genome could be ...
Metagenomic sequencing determines complete infectious bronchitis virus (avian Gammacoronavirus) vaccine strain genomes and associated viromes in chicken clinical samples.
Publication Type: Peer reviewed scientific article Authors: Steven Van Borm; Mieke Steensels; Elisabeth Mathijs; Frank Vandenbussche; Thierry van den Berg; Bénédicte Lambrecht Source: Virus Genes, ...
Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants
Keersmaecker Source: Genes, Volume 12, Issue 4 (2021) Keywords: SARS-CoV-2; COVID-19; variants; detection; RT-qPCR; in silico specificity evaluation; bioinformatics tool; WGS data; mismatches; primers and probes ...
Increased viral read counts and metagenomic full genome characterization of porcine astrovirus 4 and Posavirus 1 in sows in a swine farm with unexplained neonatal piglet diarrhea
Publication Type: Peer reviewed scientific article Authors: Steven Van Borm; Kevin Vanneste; Fu, Qiang; Maes, Dominiek; Alexandra Schoos; Eline Vallaey; Frank Vandenbussche Source: Virus Genes, ...
Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins.
haemagglutinin-neuraminidase (HN), are key factors in mumps pathogenesis and are important targets for the immune response during mumps virus infection. We compared the predicted amino acid sequences of the F and HN genes from ...
Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.
NF-κB signaling and a cysteine protease that cleaves substrates, leading to the expression of immunoregulatory genes. Here, we examined the impact of genetic or pharmacological MALT1 inhibition in mice on ...
MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.
acts as a scaffold protein for NF-κB signalling and a cysteine protease that cleaves substrates, further promoting the expression of immunoregulatory genes. Deregulated MALT1 activity has been associated ...