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Résultats de la recherche - 12 results

Insights From Early Clinical Trials Assessing Response to mRNA SARS-CoV-2 Vaccination in Immunocompromised Patients.

risk of developing severe disease. This is challenging, however, since effective mRNA vaccination requires the successful cooperation of several components of the innate and adaptive immune systems, both ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

protease that mediates the activation of several innate and adaptive immune cells in response to multiple receptors, and therapeutic MALT1 targeting is believed to be a valid approach for autoimmunity and ...

Porcine NK Cells Stimulate Proliferation of Pseudorabies Virus-Experienced CD8 and CD4CD8 T Cells.

(NK) cells belong to the innate immune system and play a central role in the defense against viral infections and cancer development, but also contribute to shaping adaptive immune responses. NK cells ...

MALT1 controls attenuated rabies virus by inducing early inflammation and T cell activation in the brain.

Steven Van Gucht Source: J Virol (2018) Keywords: MALT1 Rabies Abstract: MALT1 is involved in the activation of immune responses as well as in the proliferation and survival of certain cancer cells. MALT1 ...

Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8(+) Lymphocytes in a Heterologous Challenge Model.

T-lymphocytes. The described adaptive cellular and humoral immune responses in pigs are in line with the induced or natural infections in mice and humans. Previous studies underscored the heterogeneity of T. ...

Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.

innate responses and contributing to the development of specific adaptive immune responses. Novel adjuvants have been developed based on agonists of PRR s. Areas covered: Lipid pathogen-associated ...

Regulatory T-cell development and function are impaired in mice lacking membrane expression of full length intercellular adhesion molecule-1.

contribution of intercellular adhesion molecule-1 (ICAM-1) to adaptive immune responses, we analysed T-cell development and function in mice lacking full-length ICAM-1 (ICAM-1(tm1Jcgr)). Compared with wild-type ...

Evaluation of adaptive immune responses and heterologous protection induced by inactivated bluetongue virus vaccines.

Bluetongue Bluetongue virus Cross Protection Immunity, Heterologous Random Allocation Severity of Illness Index Sheep Vaccines, Inactivated Viral Load Viral Vaccines Viremia Abstract: Eradication of bluetongue ...

M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

Bert; Grooten, Johan; Fiers, Walter; Saelens, Xavier Source: PLoS One, Volume 8, Issue 3, p.e59081 (2013) Keywords: Adaptive Immunity Adaptor Proteins, Vesicular Transport Animals Female Humans Immunity ...

CP7_E2alf oral vaccination confers partial protection against early classical swine fever virus challenge and interferes with pathogeny-related cytokine responses.

44, p.9 (2013) Keywords: Adaptive Immunity Administration, Oral Animals Antibodies, Neutralizing Antibodies, Viral Classical Swine Fever Classical swine fever virus Cytokines Specific Pathogen-Free ...

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