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Résultats de la recherche - 15 results
The immunodominant T-cell epitopes of the mycolyl-transferases of the Antigen 85 complex of M. tuberculosis34076
candidate antigens. Ag85A and Ag85B, initially purified from Mycobacterium bovis bacillus Calmette-Guerin (BCG)/Mycobacterium tuberculosis culture filtrate respectively, induce strong T-cell proliferation and ...
T cell reactivity against mycolyl transferase antigen 85 of M. tuberculosis in HIV-TB coinfected subjects and in AIDS patients suffering from tuberculosis and nontuberculous mycobacterial infections
Keywords: 0 Acyltransferases AIDS-Related Opportunistic Infections Antigens Antigens,Bacterial article Belgium Cell Clinical complications culture developing disease electronic families Family Follow up ...
Antigen discovery: a postgenomic approach to paratuberculosis diagnosis195
the diagnosis of paratuberculosis. Two complementary approaches were implemented, the first one consisting in the systematic proteomic identification of proteins present in MAP culture filtrates (CF s), ...
Members of the 30- to 32-kilodalton mycolyl transferase family (Ag85) from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens recognized early upon infection in mice and cattle16
antigens, present abundantly in mycobacterial culture filtrate (CF), are among the well-known protective antigens of Mycobacterium tuberculosis and Mycobacterium bovis. Culture filtrate, prepared from ...
Culture filtrate specific H-2(b) restricted CD8+ T cells activated in vivo by Mycobacterium tuberculosis or bovis BCG recognize a restricted number of immunodominant peptides.
Mycobacterium tuberculosis infected mice with culture filtrate antigens leads to the appearance of a high percentage of D(b) restricted IFN gamma synthesizing CD8 + T cell blasts. Transporter associated protein-2 ...
What are the immunologically active components of bacille Calmette-Guérin in therapy of superficial bladder cancer?
Vaccine CD56 Antigen Humans Interferon-gamma Interleukin-12 Interleukin-2 Interleukin-6 Leukocytes, Mononuclear Neoplasm Proteins Th1 Cells Tumor Cells, Cultured Urinary Bladder Neoplasms Abstract: The ...
What is the optimal regimen for BCG intravesical therapy? Are six weekly instillations necessary?
instillations. MATERIALS AND METHODS: The evolution of the lymphoproliferative response of peripheral blood mononuclear cells against BCG culture filtrate (CF), tuberculin (PPD) and BCG extract (EXT) was tested ...
Cloning of the gene encoding a 22-kilodalton cell surface antigen of Mycobacterium bovis BCG and analysis of its potential for DNA vaccination against tuberculosis.
mice vaccinated with live Mycobacterium bovis BCG, we previously generated three monoclonal antibodies reactive against a 22-kDa protein present in mycobacterial culture filtrate (CF) (K. Huygen et al., ...
Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by Bacillus Calmette-Guérin vaccination in H-2b mice.
supernatant [culture filtrate (CF) antigens]. In the present study, we have further characterized the lytic activity of these CTL and the processing pathway used for the presentation of CF proteins. We show ...
Immunogenicity and protective efficacy of tuberculosis DNA vaccines encoding putative phosphate transport receptors.
Vaccines, DNA Abstract: Using culture filtrate Ag-specific mAbs generated from mycobacteria-infected H-2b haplotype mice, we have previously identified three genes in the Mycobacterium tuberculosis genome, ...