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DNA vaccines against tuberculosis.

Antigens, Bacterial BCG Vaccine Humans Immunization, Secondary Mycobacterium tuberculosis T-Lymphocytes, Cytotoxic Tuberculosis, Pulmonary Vaccination Vaccines, DNA Abstract: INTRODUCTION: Tuberculosis (TB) ...

Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.

mice Mice, Inbred C57BL Mice, Knockout T-Lymphocytes, Cytotoxic Tuberculosis Vaccines Vaccination Vaccines, DNA Abstract: Reactivation tuberculosis (TB) is a serious problem in immunocompromised ...

Absence of viral envelope proteins in equine herpesvirus 1-infected blood mononuclear cells during cell-associated viremia.

complex (MHC)-I was examined, since MHC-I assists in making infected cells recognizable for cytotoxic T-lymphocytes (CTL). Four ponies, previously exposed to EHV, and two ponies that had no contact with EHV ...

Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.

Histocompatibility Antigen H-2D Interferon-gamma Interleukin-2 mice Mice, Inbred C57BL Molecular Sequence Data Mycobacterium tuberculosis T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccines Vaccines, DNA ...

Improved tuberculosis DNA vaccines by formulation in cationic lipids.

Phosphatidylethanolamines Spleen T-Lymphocytes, Cytotoxic Th1 Cells Tuberculosis Vaccination Vaccines, DNA Abstract: Mice were vaccinated with plasmid DNA (pDNA) encoding antigen 85A (Ag85A), Ag85B, or PstS-3 from ...

What are the immunologically active components of bacille Calmette-Guérin in therapy of superficial bladder cancer?

We purified various BCG subcomponents and analyzed in vitro their ability to enhance a Th1 polarized immune response as well as to increase lymphocyte-mediated cytotoxicity against bladder tumors. ...

Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment.

Interleukin-4 Lung mice Mice, Inbred BALB C Mice, Inbred C57BL Mycobacterium tuberculosis Spleen T-Lymphocytes, Cytotoxic Tuberculosis Vaccination Vaccines, DNA Abstract: Immunogenicity and protective efficacy of ...

Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by Bacillus Calmette-Guérin vaccination in H-2b mice.

CD8-Positive T-Lymphocytes Cell Line Chloroquine Culture Media H-2 Antigens Interferon-gamma Lymphocyte Activation Membrane Glycoproteins mice Mice, Inbred C57BL Perforin Pore Forming Cytotoxic Proteins ...

Characterization of the culture filtrate-specific cytotoxic T lymphocyte response induced by bacillus Calmette-Guérin vaccination in H-2b mice

bacille Calmette-Guérin BFA Brefeldin A CF culture filtrate CTL cytotoxic T lymphocytes culture filtrate antigens cytotoxic T lymphocytes Mycobacterium bovis bacillus Calmette-Guérin TAP ...

DNA vaccines against tuberculosis.

cells, Th1 cytokines and cytotoxic T lymphocytes) and was protective in mouse and guinea pig models of mycobacterial disease. Therefore, DNA vaccination holds promise as an effective means of preventing ...

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