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The increasing significance of disease severity in a burden of disease framework

burden of disease severity distribution Years lived with disability YLD Abstract: Recent estimates have reiterated that non-fatal causes of disease, such as low back pain, headaches and depressive ...

Sex difference in innate inflammatory response and macrophage polarization in Streptococcus agalactiae-induced pneumonia and potential role of microRNA-223-3p.

biological sex is a risk factor in the incidence and severity of infection-induced inflammatory diseases, the underlying mechanisms are still poorly understood. In this study, we compared the innate ...

Mapping EQ-5D utilities to GBD 2010 and GBD 2013 disability weights: results of two pilot studies in Belgium.

attributed a relatively higher severity level to musculoskeletal disorders such as ‘Amputation of both legs’ and a relatively lower severity level to non-functional disorders such as ‘Headache migraine’ ...

Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock90

in conditions associated with an increased volume of distribution (Vd), such as severe sepsis and septic shock. The primary aim of this study was to determine whether 25 mg/kg (total body weight) of ...

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