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Résultats de la recherche - 35 results
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...
Mixtures of genotoxicants: does the principle of additivity apply?
Belgium (2023) Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics: Food consumption and food safety Consommation et sécurité alimentaires Voedselconsumptie en ...
Mixtures of genotoxicants: does the principle of additivity apply?
Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de ...
The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells
Source: EEMGS meeting, Malaga, Spain (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid ...
Development of an AOP-based IATA for genotoxicity
O Armant; C Pachoulide; H Bouwmeester; G Raitano; E Benfenati; E Wyrzykowska; M Stepnik; T Puzyn; M Audebert; Birgit Mertens Source: EEMGS meeting (2023) Keywords: adverse outcome pathways genotoxicity ...
The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment
SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de ...
GENOMARK, a promising new approach methodology for genotoxicity testing in the cosmetic industry
International cosmetic congress, Antalya, Turkey (2022) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation ...
In silico methods for chromosome damage
Issue 8, New York (2022) ISBN: 978-1-0716-1960-5 Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological endpoint in each regulatory setting with respect ...
Chemical and toxciological characterization of e-liquid cigarettes
through e-cigarette use. In the final experimental part of the thesis, we focused on the identification of potential genotoxic flavouring substances in e-liquids through the use of non-animal methodologies. ...
Biological evaluation of diazene derivatives as anti-tubercular compounds.
three compounds showed signs of genotoxicity by VITOTOX or by Comet assay. The study was complemented by demonstration of the inhibition of intracellular replication of M.tb H37R v inside J774 A.1 cells ...