Résultats de la recherche - 11 results

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Publication Type: Scientific poster, presentation or proceeding Authors: An Van den Bossche; Roby Bhattacharyya; Jean-Yves Coppee; Leen Rigouts; Alain Baulard; Deborah Hung; Vanessa Mathys; ...

Evaluation of Non-Tuberculous Mycobacteria identification with maldi-tof mass spectrometry by applying sonication: a multicenter study

Publication Type: Scientific poster, presentation or proceeding Authors: EU Mycobacteria-MALDI study group; An Van den Bossche; Pieter-Jan Ceyssens Source: ECCMID 2018, Issue ESCMID, Madrid, Spain ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

cultures. In total 88.6% (172/194) of the samples were correctly identified on the species-level using a cut-off score of 1.8 and 91.75% (178/194) using a cut-off of 1.65. All samples of the Mycobacterium ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

cluster genes was noted. This can be assigned to the dependence of isoniazid target inhA on NADH. Lowering the ndh-activity is also seen in resistant strains.   Conclusions: By using RNA tag-seq, a global ...

MALDI-TOF for the Identification and Drug Sensitivity Testing of Mycobacteria

Publication Type: Scientific poster, presentation or proceeding Authors: Pieter-Jan Ceyssens Source: Hot Topics in Microbiology- Join the Grapevine, BRITISH SOCIETY FOR MICROBIAL TECHNOLOGY, Volume ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

synthase II) complex, which is targeted by isoniazid. On the other hand, a remarkable down-regulation of the NADH-dehydrogenase (ndh) cluster genes was noted. This can be assigned to the dependence of ...

Multicentric study on the improved identification of Non-Tuberculous Mycobacteria with MALDI-TOF MS using three different preprocessing protocols

Publication Type: Scientific poster, presentation or proceeding Authors: EU Mycobacteria-MALDI study group; An Van den Bossche; Pieter-Jan Ceyssens Source: ECCMID 2017, Issue ESCMID, Vienna, Austria ...

WIV-ISP's experiences in the use of MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

Publication Type: Scientific poster, presentation or proceeding Authors: An Van den Bossche; Pieter-Jan Ceyssens Source: FARES/VRGT, FARES/VRGT Brussels, Belgium (2016) Keywords: drug susceptibility ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

drug and RNA-targeting probes were designed. Next, the RNA-based DST was developed in 96 well format. In short, 200 µl of a positively flagged MGITTM (BD) culture is spiked with a drug, while a replicate ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

Publication Type: Scientific poster, presentation or proceeding Authors: An Van den Bossche; Hugo Varet; Amandine Sury; Odile Sismeiro; Rachel Legendre; Jean-Yves Coppee; Vanessa Mathys; Pieter-Jan ...

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