Résultats de la recherche - 10 results
Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants.
a mutation such as E119V- NA is known, highly sensitive PCR-based genotypic assays can be used to identify the prevalence of such mutant influenza viruses in clinical samples. In this study, based on an ...
Next-Generation Sequencing: An Eye-Opener for the Surveillance of Antiviral Resistance in Influenza
antiviral resistance INFLUENZA Next-generation sequencing Surveillance Abstract: Next-generation sequencing (NGS) can enable a more effective response to a wide range of communicable disease threats, such as ...
Real-time prediction of influenza outbreaks in Belgium.
epidemic. This surveillance network reports the weekly incidence of influenza-like illness (ILI) cases, which makes it possible to detect the epidemic onset, as well as other characteristics of the epidemic ...
Bigger and Better? Representativeness of the Influenza A Surveillance Using One Consolidated Clinical Microbiology Laboratory Data Set as Compared to the Belgian Sentinel Network of Laboratories.
globally, while the need for reliable and representative surveillance systems remains as acute as ever. The public health surveillance of infectious diseases uses reported positive results from sentinel ...
Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans
humans. This suggests that UPS hijacking underlies the efficient infection of humans and can be used as an indicator for evaluation of the potential of avian IAV s to infect humans. Several UPS factors were ...
Survey on the Use of Whole-Genome Sequencing for Infectious Diseases Surveillance: Rapid Expansion of European National Capacities, 2015-2016.
vaccine-preventable diseases identified as priorities for European genomic surveillance. Twenty-eight and twenty-nine out of the 30 EU / EEA countries participated in the survey in 2015 and 2016, respectively. National ...
Overlapping signals for translational regulation and packaging of influenza A virus segment 2.
mutated AUG s 1-4 and monitored polypeptide synthesis from plasmids and recombinant viruses. This identified sORF2 as a key regulatory element with opposing effects on PB1- F2 and PB1- N40 expression. We ...
Non coding extremities of the seven influenza virus type C vRNA segments: effect on transcription and replication by the type C and type A polymerase complexes.
transcription/replication of the influenza viruses implicate the terminal nucleotide sequences of viral RNA, which comprise sequences at the extremities conserved among the genomic segments as well as variable 3' and ...
The impact of regular school closure on seasonal influenza epidemics: a data-driven spatial transmission model for Belgium.
Dis, Volume 18, Issue 1 (2018) Abstract: BACKGROUND: School closure is often considered as an option to mitigate influenza epidemics because of its potential to reduce transmission in children and then ...
A general approach to identify low-frequency variants within influenza samples collected during routine surveillance.
% were established as detection limits. Secondly, a subset of 59 retained influenza A (H3N2) samples from the 2016-2017 Belgian influenza season was composed. Thirdly, as a proof of concept for the added ...