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In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Johan; Goris, Nesya Source: Antiviral Res, Volume 105, p.59-63 (2014) Keywords: Animals Antiviral Agents Aphthovirus Benzimidazoles Cattle Cell Line Cercopithecus aethiops Cytidine Cytopathogenic Effect, ...

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

enterovirus 3C(pro) but also 3C(pro) of foot-and-mouth disease virus (FMDV), an aphthovirus. In contrary, AG7404 (compound 1), an analogue of AG7088, had no effect on FMDV 3C(pro) activity, for which we provide ...

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