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Résultats de la recherche - 25 results
Isoniazid Bactericidal Activity Involves Electron Transport Chain Perturbation.
inhibition. The activity of isoniazid (INH), a key first-line bactericidal antituberculosis drug currently known to inhibit mycolic acid synthesis, becomes extremely poor under stress conditions, such as ...
Y-box-binding protein 1 supports the early and late steps of HIV replication.
replication. YB-1 depletion resulted in a 10-fold decrease in HIV-1 replication in different cell lines. Dissection of the replication defects revealed that knockdown of YB-1 is associated with a 2- to 5-fold ...
Porcine NK Cells Stimulate Proliferation of Pseudorabies Virus-Experienced CD8 and CD4CD8 T Cells.
are particularly important in the first line defense against herpesviruses, including alphaherpesviruses. In addition to their ability to kill target cells and produce interferon-γ, porcine and human NK ...
A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment
for pharmaceutical, chemical, and consumer products, as afflicted compounds have to be (prematurely) abandoned or further tested on animals. Using the metabolically competent human HepaRG ™ cell line and toxicogenomics ...
Strain- and Dose-Dependent Reduction of Toxoplasma gondii Burden in Pigs Is Associated with Interferon-Gamma Production by CD8(+) Lymphocytes in a Heterologous Challenge Model.
Publication Type: Peer reviewed scientific article Authors: Jennes, Malgorzata; Stéphane De Craeye; Devriendt, Bert; Katelijne Dierick; Dorny, Pierre; Cox, Eric Source: Front Cell Infect Microbiol, ...
The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells.
Publication Type: Peer reviewed scientific article Authors: Verloes, A; Spits, C; Vercammen, M; Geens, M; LeMaoult, J; Sermon, K; Wim Coucke; Van de Velde, H Source: Stem Cell Res, Volume 19, ...
Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.
Viral Base Sequence Bluetongue Bluetongue virus Capsid Proteins Cattle Cell Line Drug Stability Drug Storage Female Male Reverse Genetics Serogroup Sheep Vaccination Vaccines, Attenuated Vaccines, Subunit ...
Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays.
Demaegdt; Mertens, Birgit; Karine Vandermeiren; Scippo, Marie-Louise; Elskens, Marc Source: Toxicol In Vitro, Volume 37, p.121-133 (2016) Keywords: Animals Biological Assay Bottle Feeding Cell Line Cell Line ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
Issue 9, p.2215-29 (2016) Keywords: Carcinogens Cell Line, Tumor Computational Biology Dose-Response Relationship, Drug Gene Expression Profiling Gene Expression Regulation Genome-Wide Association Study ...
Post-exposure Treatment with Anti-rabies VHH and Vaccine Significantly Improves Protection of Mice from Lethal Rabies Infection.
8, p.e0004902 (2016) Keywords: Animals Antibodies, Neutralizing Antibodies, Viral Cell Line Disease Models, Animal Female Half-Life Humans mice Neutralization Tests Post-Exposure Prophylaxis Rabies ...