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Porcine NK Cells Stimulate Proliferation of Pseudorabies Virus-Experienced CD8 and CD4CD8 T Cells.

are particularly important in the first line defense against herpesviruses, including alphaherpesviruses. In addition to their ability to kill target cells and produce interferon-γ, porcine and human NK ...

Replication-Deficient Particles: New Insights into the Next Generation of Bluetongue Virus Vaccines.

Viral Base Sequence Bluetongue Bluetongue virus Capsid Proteins Cattle Cell Line Drug Stability Drug Storage Female Male Reverse Genetics Serogroup Sheep Vaccination Vaccines, Attenuated Vaccines, Subunit ...

Pseudorabies virus isolates from domestic pigs and wild boars show no apparent in vitro differences in replication kinetics and sensitivity to interferon-induced antiviral status.

strain. Replication kinetics and plaque formation capacity in continuous swine testicular cells and different primary porcine cell lines were highly similar for isolates from both populations. Treatment of ...

Small RNA deep sequencing identifies viral microRNAs during malignant catarrhal fever induced by alcelaphine herpesvirus 1.

a lymphoblastoid cell line propagated from a calf infected with AlHV-1 and developing MCF. Among the sequenced candidate miRNAs, 32 were expressed on the reverse strand of the genome in two main clusters. The ...

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.

King, Donald P; Neyts, Johan; Kris De Clercq Source: Biochem Biophys Res Commun, Volume 455, Issue 3-4, p.378-81 (2014) Keywords: Animals Antiviral Agents Benzimidazoles Cell Line Cell Survival ...

In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Johan; Goris, Nesya Source: Antiviral Res, Volume 105, p.59-63 (2014) Keywords: Animals Antiviral Agents Aphthovirus Benzimidazoles Cattle Cell Line Chlorocebus aethiops Cytidine Cytopathogenic Effect, ...

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

Agents Cell Line Cysteine Endopeptidases Drug Evaluation, Preclinical Genes, Reporter Humans Luciferases, Firefly Picornaviridae Protease Inhibitors Viral Proteins Abstract: Proteolytical cleavage of the ...

In vitro and in vivo infectious potential of coxiella burnetii: a study on Belgian livestock isolates.

6, p.e67622 (2013) Keywords: Animals Cattle Cell Line Cell Line, Tumor Coxiella burnetii Female Genotype Goats HeLa Cells Humans Livestock mice Mice, Inbred BALB C Netherlands Q Fever Abstract: Q-fever ...

Proteomic characterization of murid herpesvirus 4 extracellular virions.

Gillet, Laurent Source: PLoS One, Volume 8, Issue 12, p.e83842 (2013) Keywords: Animals Capsid Cell Line Cricetinae Extracellular Space Glycosylation Mass Spectrometry Proteomics Rhadinovirus Viral Proteins ...

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