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Inflammatory Properties and Adjuvant Potential of Synthetic Glycolipids Homologous to Mycolate Esters of the Cell Wall of Mycobacterium tuberculosis.

(2017) Keywords: a acid Acids Activation an analysi analysis article AS Belgium Brussels Cell Cell Wall cells Class Cytokines disease Diseases electronic Glucose GMM health Hypothesis Immunisation ...

Humoral and cell mediated immune responses to a pertussis containing vaccine in pregnant and nonpregnant women.

tetanus toxin (TT) and diphtheria toxin (DT) antibodies were measured by ELISA. Cellular immune responses were analyzed using a diluted whole blood assay, measuring proliferation, and cytokine release in ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

mycobacteria specific IFN-γ producing CD4 (+) and particularly CD8 (+) T cells could be detected by intracellular cytokine staining in mice vaccinated with the M.tb mutants. Finally, vaccination with either of ...

Immunogenicity and protective efficacy of tuberculosis subunit vaccines expressing PPE44 (Rv2770c).

Vaccine, Volume 26, Issue 48, p.6053-63 (2008) Keywords: Adjuvants, Immunologic Amino Acid Sequence Animals Antibodies, Bacterial Antibody Formation Antigens, Bacterial BCG Vaccine Cytokines Dna Epitopes ...

Immunogenicity and protective efficacy of DNA vaccines encoding MAP0586c and MAP4308c of Mycobacterium avium subsp. paratuberculosis secretome.

Jean-Jacques; Wattiez, Ruddy; Huygen, Kris Source: Vaccine, Volume 26, Issue 37, p.4783-94 (2008) Keywords: Animals Antibodies, Bacterial Bacterial Proteins Cytokines Epitope Mapping Epitopes, T-Lymphocyte Female ...

Evaluation of the immunogenicity of pBudCE4.1 plasmids encoding mycolyl-transferase Ag85A and phosphate transport receptor PstS-3 from Mycobacterium tuberculosis.

single antigens on pBudCE4.1 or pV1J.ns-tPA backbone. Antibody and Th1 type cytokine responses against Ag85A were comparable, whereas responses against PstS-3 were clearly lower in mice vaccinated with the ...

Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.

Issue 5, p.2751-9 (2006) Keywords: Acyltransferases Animals Antibodies, Bacterial Antigens, Bacterial Antigens, CD4 Bacterial Proteins CD4-Positive T-Lymphocytes Cytokines Female Interferon-gamma Lung ...

Induction of in vivo functional Db-restricted cytolytic T cell activity against a putative phosphate transport receptor of Mycobacterium tuberculosis.

cytokine levels, whereas mice of H-2(d, k, r, s, and q) haplotype were completely unreactive. Low responsiveness against PstS-3 in MHC class II mutant B6.C-H-2(bm12) mice could be overcome by DNA ...

CD4+ T cells contain Mycobacterium tuberculosis infection in the absence of CD8+ T cells in mice vaccinated with DNA encoding Ag85A.

cytokines similar to wild-type mice. Although beta2m-/- mice were more susceptible to M. tuberculosis infection, following vaccination they efficiently controlled bacterial replication in spleen and lungs ...

Cross-reactive immune responses against Mycobacterium bovis BCG in mice infected with non-tuberculous mycobacteria belonging to the MAIS-Group.

and C57BL /6, were infected intravenously with Mycobacterium intracellulare, M. avium or M. scrofulaceum and monitored during 3 months for mycobacterial replication and antibody and Th1-type cytokine ...

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