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Résultats de la recherche - 4 results

Controlled Human Infection Studies: Proposals for guidance on how to design, develop and produce a challenge strain.

followed by use of qualified methods to test critical steps in the manufacturing process, or the final product itself. These activities are complementary: GMP rules, which intervene only at the time of the ...

Chemical and toxciological characterization of e-liquid cigarettes

As such, 807 flavouring substances were identified in 129 e-liquids using complementary HS- GC MS methods. In a first step, all these substances were screened for genotoxicity using qualitative and ...

Identification of Flavouring Substances of Genotoxic Concern Present in E-Cigarette Refills

investigated in silico with two complementary (quantitative) structure-activity relationship ((Q) SAR) models (Derek Nexus, Sarah Nexus). In total, 57 flavouring components were identified with a structural ...

Detection and risk evaluation of counterfeit medicines based on physico-chemical properties: the fingerprint and chemometrics approach

fingerprints for a Viagra® and a Cialis® sample set. These fingerprints were included in the chemometric data analysis, aiming to test whether PDA and MS are complementary detection techniques. This extensive ...

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