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Résultats de la recherche - 7 results

Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid

incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...

Commentary on the MID3 Good Practices Paper.

need for harmonization on good M&S practices and for continuing dialog across all parties. The MSWG acknowledges the initiative of the EFPIA Model-Informed Drug Discovery and Development (MID3) group ...

In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.

Viral Drug Discovery Foot-and-Mouth Disease Models, Theoretical Ribavirin RNA, Viral Virus Cultivation Virus Replication Abstract: Foot-and-mouth disease virus (FMDV) is a highly pathogenic member of the ...

Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection36574

properties together with the ease of manipulation, relatively low cost and well established use of rats in toxicology and pharmacokinetic analyses make the rat a good animal model for TB drug discovery ...

Transcriptional profiling of Mycobacterium tuberculosis suggests respiratory poisoning upon exposure to delamanid

incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...

Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid.

incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...

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