Résultats de la recherche - 38 results
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid
incidence and counter the spread of multidrug resistant TB, the discovery and characterization of new drugs is essential. In this study, the transcriptional response of two Mycobacterium tuberculosis strains ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...
Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing
susceptibility to first-line antituberculosis drugs has not been clear. METHODS: We obtained whole-genome sequences and associated phenotypes of resistance or susceptibility to the first-line antituberculosis ...
A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.
profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...
Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.
Volume 22, Issue 1 (2018) Keywords: Carbapenems repurposed drugs XDR-TB Abstract: BACKGROUND: Extensively drug-resistant tuberculosis (XDR- TB), defined as TB caused by a Mycobacterium strain resistant to ...
Survey on the Use of Whole-Genome Sequencing for Infectious Diseases Surveillance: Rapid Expansion of European National Capacities, 2015-2016.
epidemiology of infectious diseases and antimicrobial drug resistance. It provides precise geographical delineation of spread and enables incidence monitoring of pathogens at genotype level. Coupled with ...
Molecular epidemiology of Mycobacterium tuberculosis complex in Brussels, 2010-2013.
Resistance, Multiple, Bacterial Emigrants and Immigrants Family Health Female Genetic Variation Genotype Hospitals, Urban Humans incidence Male middle aged Mycobacterium tuberculosis Phylogeny Population ...
Public health risk of antimicrobial resistance transfer from companion animals.
Volume 72, Issue 4, p.957-968 (2017) Keywords: Animals bacteria Bacterial Infections Disease Transmission, Infectious Drug Resistance, Bacterial Humans Pets Risk Assessment Zoonoses Abstract: ...
Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
length and nucleotide sequence vary between bacterial species, including mycobacteria. Mutations in the rpoB gene alter the structure of this protein and cause drug resistance. To describe the ...
Antimicrobial resistance surveillance in Escherichia coli by using normalized resistance interpretation.
p.1-7 (2016) Keywords: Animals Anti-Bacterial Agents Drug Resistance, Bacterial Escherichia coli Escherichia coli Infections Microbial Sensitivity Tests Swine Swine Diseases Abstract: OBJECTIVES: To ...