Résultats de la recherche - 26 results

Insights From Early Clinical Trials Assessing Response to mRNA SARS-CoV-2 Vaccination in Immunocompromised Patients.

lower response to the vaccine such as anti- CD19, anti- CD20 or anti- CD38 therapies, low (naive) CD4 T-cell counts, genetic or therapeutic Bruton tyrosine kinase deficiency, treatment with ...

The lack of K13-propeller mutations associated with artemisinin resistance in Plasmodium falciparum in Democratic Republic of Congo (DRC).

Republic of the Congo Drug Resistance Female Humans Malaria, Falciparum Male middle aged Mutation Plasmodium falciparum Polymorphism, Genetic Young adult Abstract: Artemisinin-based combination therapies ...

Collaborative data collection by TREAT-NMD Registries to support post-marketing surveillance in Spinal Muscular Atrophy

atrophy (SMA) is a rare genetic neuromuscular disorder characterized by a loss of motor neurons in the spinal cord and the brainstem, leading to muscle weakness and atrophy. The estimated incidence is ...

Imported malaria and artemisinin-based combination therapy failure in travellers returning to Belgium: A retrospective study.

residents. Here, we describe recent trends of imported malaria to Belgium and characterize the first cases of P.falciparum failure to artemisinin-based combination therapy (ACT). METHODS: National surveillance ...

Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.

Françoise Benoit-Vical; Pierrette Melin; Patrick De Mol; Marie-Pierre Hayette Source: PLoS One, Volume 12, Issue 6 (2017) Keywords: Artemisinins Democratic Republic of the Congo Drug Resistance Drug Therapy ...

The TREAT-NMD DMD Global Database: analysis of more than 7,000 Duchenne muscular dystrophy mutations

Databases Development Diagnostics disease Diseases Duchenne muscular dystrophy electronic Frequency Genetic Genetic Therapy global im Institute IS journal Medicine Muscular Dystrophies Muscular dystrophy ...

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

(e.g., poliovirus, coxsackievirus, rhinovirus, and enterovirus 71) for which no antiviral drugs are available. The viral RNA-dependent RNA polymerase is an attractive target for antiviral therapy ...

New challenges in perioperative management of pancreatic cancer.

Devière; Jean-Luc Van Laethem Source: World J Gastroenterol, Volume 21, Issue 8 (2015) Keywords: Biomarkers, Tumor Carcinoma, Pancreatic Ductal Chemotherapy, Adjuvant Humans Neoadjuvant Therapy Neoplasm ...

Engineering nucleases for gene targeting: safety and regulatory considerations.

(2014) Keywords: Deoxyribonucleases Gene Targeting Genetic Therapy Humans SAFETY Abstract: Nuclease-based gene targeting (NBGT) represents a significant breakthrough in targeted genome editing since it is ...

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