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Allergic Asthma Favors Growth in the Lungs of Infected Mice.

dense aggregates of infected cells composed mainly of alveolar macrophages (CD11 c F4 /80 MHCII) surrounded by neutrophils (Ly-6G). Asthma-induced susceptibility appears to be dependent on CD4 T cells, ...

Short-term biodistribution and clearance of intravenously administered silica nanoparticles

takes more time due to hepatic processing and biliary excretion. In treated animals the liver showed in addition a prominent increase of macrophages between both evaluation moments. Within the first 24 ...

Impact of caspase-1/11,-3,-7, or IL-1/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease.

Cell Death Discov, Volume 3, p.17012 (2017) Abstract: Rabies virus is a highly neurovirulent RNA virus, which causes about 59000 deaths in humans each year. Previously, we described macrophage ...

Oxidative stress pathways involved in cytotoxicity and genotoxicity of titanium dioxide (TiO2) nanoparticles on cells constitutive of alveolo-capillary barrier in vitro.

examined on cell lines representative of alveolo-capillary barrier. The present study showed that all nanoparticle-exposed cell lines displayed ROS generation. Macrophage-like THP-1 and HPMEC- ST1.6R ...

Synthesis and anti-tubercular activity of N(2)-arylbenzo[g]isoquinoline-5,10-dione-3-iminium bromides.

Abbaspour Tehrani, K Source: Org Biomol Chem, Volume 14, Issue 6, p.2041-51 (2016) Keywords: Antitubercular Agents Dose-Response Relationship, Drug Hydrocarbons, Brominated Isoquinolines Macrophages Microbial ...

Overexpression of DosR in Mycobacterium tuberculosis does not affect aerobic replication in vitro or in murine macrophages

Issue 2, Number 720, p.713- 720 (2015) ISBN: 1590-4261 Keywords: a Affect AS bacteria conditions Control culture Culture Media DosR expression gene Genes growth IT Latency M Macrophage Macrophages MEDIA ...

CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells.

Interferon Regulatory Factors Interleukin-12 Interleukin-17 Intestinal Mucosa Macrophages mice Mice, Transgenic Monocytes Phagocytes Phenotype Receptors, CCR2 T-Lymphocyte Subsets Th17 Cells Abstract: The ...

Anti-mycobacterial activity of 1,3-diaryltriazenes.

Macrophages mice Microbial Sensitivity Tests Molecular Structure Mycobacterium avium Mycobacterium bovis Mycobacterium ulcerans Structure-Activity Relationship Triazenes Abstract: The rapid generation and ...

2,4-Dialkyl-8,9,10,11-tetrahydrobenzo[g]pyrimido[4,5-c]isoquinoline-1,3,7,12(2H,4H)-tetraones as new leads against Mycobacterium tuberculosis.

Norbert Source: Eur J Med Chem, Volume 77, p.409-21 (2014) Keywords: Animals Antitubercular Agents Cell Line Dose-Response Relationship, Drug Isoquinolines Macrophages mice Microbial Sensitivity Tests ...

Biological evaluation of diazene derivatives as anti-tubercular compounds.

examined for acute cell toxicity on a murine macrophage like monocyte cell line J774 A.1 in which the cell viability was reduced by 50% at concentrations ranging from 7.4 μg/mL to 20.7 μg/mL. Neither of the ...

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