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In Silico Methods for Chromosome Damage.

Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...

Deepening of In Silico Evaluation of SARS-CoV-2 Detection RT-qPCR Assays in the Context of New Variants

above 99%. Additionally, some mutations specific to new SARS-CoV-2 variants of concern were found to be located in oligonucleotide annealing sites. This might impact the strategy to be considered for ...

Isolation and characterization of the compounds responsible for the antimutagenic activity of Combretum microphyllum (Combretaceae) leaf extracts

n-Tetracosanol Abstract: BACKGROUND: Mutations play a major role in the pathogenesis and development of several chronic degenerative diseases including cancer. It follows, therefore that antimutagenic compound may ...

The Vitotox and ToxTracker assays: a two-test combination for quick and reliable assessment of genotoxic hazards

Source: Mutation research, Volume 810, Number 21 (2016) Keywords: an analysi analysis approach AS assessment chemicals Combination cosmetic Development Europe Follow up FOLLOW-UP genotoxicity hazard health ...

Scientific opinion on Malachite green in food

Mutation occurrence ON PRODUCTS public public health Public-health RANGE rats response risk survey surveys THYROID Type use Weight Abstract: Malachite green (MG) has been used globally in aquaculture but is ...

Combretum microphyllum and Leucospermum erubescens inhibit the genotoxic effects of 4-NQO, MMC and EMS in vitro

Mutation ON pharmacology plant Plants prevention programme public public health Public-health Research response Reversal Role Salmonella Salmonella typhimurium Science study Test Toxicology Universities ...

Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species

metabolic activation. All extracts demonstrated a strong antimutagenic effect on the mutations induced by 4NQO, decreasing its mutagenic effect in a dose-dependent manner. Strong cytotoxic effects were ...

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