Résultats de la recherche - 207 results

Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine36497

compounds for the treatment of tuberculosis remains of utmost importance in the fight against the disease. Despite many efforts, the weakly gram positive Mycobacterium tuberculosis keeps demanding its toll in ...

Para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis33991

genetics identification im Institute IS IT journal Laboratories mechanism metabolism Mutation Mycobacterium Mycobacterium tuberculosis Pa PAS pharmacokinetics pharmacology prevent Prodrugs protein Proteins ...

Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice1377

(2013) Keywords: a Antigens Cell cells challenge enterotoxin Escherichia coli IL-17A immune response Immunization INFECTION Inflammation IS IT LEVEL levels Lipid A Lung M mice Mycobacterium Mycobacterium ...

From multidrug- to extensively drug-resistant tuberculosis: upward trends as seen from a 15-year nationwide study.

Male Mutation Mycobacterium tuberculosis REGISTRIES Treatment Outcome Tuberculosis, Multidrug-Resistant Young adult Abstract: BACKGROUND: Emergence of extensively drug-resistant tuberculosis (XDR- TB) ...

M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.

Mutation Mycobacterium bovis Mycobacterium tuberculosis Mycolic Acids Organ Specificity Oxygen Species Specificity Spleen Th1 Cells Th17 Cells Trachea Treatment Outcome Tuberculosis Vaccination virulence ...

Clinical value of IS6110-based loop-mediated isothermal amplification for detection of Mycobacterium tuberculosis complex in respiratory specimens

isolation & purification IT journal medical Medicine method methods microbiology Molecular Typing Mycobacterium Mycobacterium tuberculosis Nucleic Acid Amplification Techniques objectives ON p Patient ...

Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery34028

INFECTION Inflammation Institute IS IT journal LEVEL levels Lung M methods mice Mice,Inbred BALB C microbiology Mycobacterium Mycobacterium tuberculosis Oligodeoxyribonucleotides Phenotype Poloxamer ...

Biological evaluation of bisbenzaldehydes against four Mycobacterium species.

Cultured Dose-Response Relationship, Drug Drug Resistance, Bacterial Hepatocytes Host-Pathogen Interactions Humans Macrophages mice Microbial Sensitivity Tests Molecular Structure Mycobacterium Mycobacterium ...

Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis34032

Injections,Intradermal Injections,Intralymphatic Injections,Subcutaneous intradermal IS journal Lymph Nodes lymphocyte Lymphocytes M methods mice Mice,Inbred C57BL Mycobacterium Mycobacterium bovis Mycobacterium ...

Failure of PCR-Based IS6110 analysis to detect vertebral spondylodiscitis caused by Mycobacterium bovis34026

Failure genetics hospital Humans im IS isolation & purification journal Male methods microbiology Mycobacterium Mycobacterium bovis polymerase chain reaction report reports SB- IM strain ...

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