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Development of strain-level shotgun metagenomics approaches to detect and characterize microbiological contaminants in the context of food safety

sample preparation methods allowed to obtain a full characterization to strain level of the spiked strain in the beef sample, carrying another non-pathogenic strain of E.coli. The simplest protocol was ...

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test.

concentration, catalytic and biological activities. For BoNT/A₁, B₁ and E₁, serotypes pathogenic to humans, the catalytic activity and the precise protein concentration were determined by Endopep-mass spectrometry ...

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