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Assessing the receptor-mediated activity of PAHs using AhR-, ERα- and PPARγ- CALUX bioassays

activity whilst B(a)P exhibited both agonistic and antagonistic activity (lowering E2 activity by 30%). Phenanthrene and anthracene had weak ER α agonist activities. These results indicate that certain PAH ...

Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays

significant agonistic activity. 3) The ERE- CALUX: So far, only preliminary range finding results were obtained, showing that phenanthrene, naphthalene, chrysene, fluoranthene and pyrene all show agonistic ...

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