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The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa

urgently needed to develop alternative therapies. One path explored in this article is the use of bacteriophages and, more specifically, phage-derived proteins. In this study, a phage-derived protein was ...

The bacteriophage LUZ24 "Igy" peptide inhibits the Pseudomonas DNA gyrase.

replication and serves as a target for multiple antibiotics, including the fluoroquinolones. Despite it being a valuable antibiotics target, resistance emergence by pathogens including Pseudomonas aeruginosa ...

High coverage metabolomics analysis reveals phage-specific alterations to Pseudomonas aeruginosa physiology during infection.

Lavigne, Rob Source: ISME J, Volume 10, Issue 8, Number 1835, p.1823-35 (2016) Keywords: Genome, Viral Metabolomics Myoviridae Pseudomonas aeruginosa Pseudomonas Phages Abstract: Phage-mediated metabolic ...

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome.

Molecular Multienzyme Complexes Polyribonucleotide Nucleotidyltransferase Protein Binding Protein Conformation Protein Multimerization Pseudomonas aeruginosa Pseudomonas Phages RNA Helicases Viral Proteins ...

The search for therapeutic bacteriophages uncovers one new subfamily and two new genera of Pseudomonas-infecting Myoviridae.

Volume 10, Issue 1, p.e0117163 (2015) Keywords: Animals DNA, Viral Genome, Viral mice Myoviridae Phylogeny Pseudomonas aeruginosa Pseudomonas Infections Pseudomonas Phages Tandem Mass Spectrometry ...

Functional elucidation of antibacterial phage ORFans targeting Pseudomonas aeruginosa

Pseudomonas-infecting phages and selected 26 unknown, early phage ORF ans. By expressing their encoded proteins individually in the host bacterium Pseudomonas aeruginosa, we identified and further characterized six ...

Systematic identification of hypothetical bacteriophage proteins targeting key protein complexes of pseudomonas aeruginosa

Minakhin,L.; Severinov,K.; J.P. Noben; Lavigne,R. Source: Journal of Proteome Research, Volume 13, Issue 10, Number 4456, p.4446- 4456 (2014) Keywords: Bacteriophages MALDI-TOF MS Pseudomonas aeruginosa ...

Development of giant bacteriophage phiKZ is independent of the host transcription apparatus

Institute IS IT journal Laboratories map metabolism microbiology Molecular ON Operon Paper physiology protein Proteins Pseudomonas Pseudomonas aeruginosa Pseudomonas Phages Research Research Support Rna ...

Characterization of newly isolated lytic bacteriophages active against Acinetobacter baumannii.

Pseudomonas aeruginosa phages, Acibel007 belongs to the well-characterized genus of the Phikmvlikevirus. The newly isolated phages can serve as potential candidates for phage cocktails to control A. ...

A multifaceted study of Pseudomonas aeruginosa shutdown by virulent podovirus LUZ19

pathogen Pseudomonas aeruginosa under attack by one its most common predators, the Phikmvlikevirus. By analyzing various stages of infection at different levels, this study uncovers new features of phage ...

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