Résultats de la recherche - 6 results
The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.
107/15,667 (0·7%) were deemed consistent with susceptibility. For rifampicin, isoniazid, ethambutol, fluoroquinolones, and streptomycin, the mutations’ pooled sensitivity was >80%. Specificity was over 95% ...
Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.
a new software implementation. Improvements include i) an updated mutation catalogue giving greater sensitivity to detect pyrazinamide resistance, ii) support for user-defined resistance catalogues, iii) ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
Moreover, comparing the response of sensitive and resistant strains can yield additional information, like the activation of specific efflux pumps. However, due to the high cost of RNA seq analyses, genome ...
MALDI-TOF for the Identification and Drug Sensitivity Testing of Mycobacteria
Publication Type: Scientific poster, presentation or proceeding Authors: Pieter-Jan Ceyssens Source: Hot Topics in Microbiology- Join the Grapevine, BRITISH SOCIETY FOR MICROBIAL TECHNOLOGY, Volume 32, Issue BRITISH SOCIETY FOR MICROBIAL TECHNOLOGY, PHE, ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
sensitive and resistant strains can yield additional information, like the activation of specific efflux pumps. However, due to the high cost of RNA seq analyses, genome wide transcriptional analyses of drug ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
phenotypic Drug Susceptibility Testing (DST). To counter this, new fast and sensitive DNA-based methods were successfully introduced over the last years. However, these (a) are based on the knowledge on ...