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Résultats de la recherche - 54 results
Persistence of the protective immunity and kinetics of the isotype specific antibody response against the viral nucleocapsid protein after experimental Schmallenberg virus infection of sheep.
determined with virus neutralization tests (VNT) and ELISA s. The primo SBV infection protected ewes against clinical signs, viraemia and virus replication in organs upon challenge infections more than ...
A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.
Foot-and-Mouth Disease Foot-and-Mouth Disease Virus Mutation Sequence Analysis, DNA Serogroup Swine Thiazepines Virus Replication Abstract: The stamping-out policy for the control of foot-and-mouth disease virus ...
Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.
Dis, Volume 61, Issue 6, p.e89-91 (2014) Keywords: Animals Antiviral Agents Cytidine Disease Models, Animal Foot-and-Mouth Disease Foot-and-Mouth Disease Virus mice Mice, SCID RNA, Viral Abstract: Recent ...
Schmallenberg virus circulation in culicoides in Belgium in 2012: field validation of a real time RT-PCR approach to assess virus replication and dissemination in midges.
Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Viral Virus Replication Abstract: Indigenous Culicoides biting midges are suggested to be putative vectors for the recently emerged Schmallenberg ...
Experimental Schmallenberg virus infection of pigs.
from indoor housed domestic pigs (n=106). In conclusion, SBV infection of pigs can induce seroconversion but is ineffective in terms of virus replication and transmission indicating that pigs have no ...
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Drug Resistance, Viral Enzyme Inhibitors Hepacivirus Models, Molecular Mutation Protein Conformation Pyridines RNA Replicase Virus Replication Abstract: 2,6-Bis(benzimidazol-2-yl)pyridine (BBP / CSFA-0) ...
In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.
Viral Drug Discovery Foot-and-Mouth Disease Models, Theoretical Oximes Ribavirin RNA, Viral Sulfonamides Virus Cultivation Virus Replication Abstract: Foot-and-mouth disease virus (FMDV) is a highly ...
Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.
picornaviral polyprotein is essential for viral replication. Therefore, viral proteases are attractive targets for anti-viral therapy. Most assays available for testing proteolytical activity of proteases are ...
Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep.
Outbreaks Europe Female Reassortant Viruses RNA, Viral Serotyping Sheep, Domestic Vaccines, Subunit Viral Vaccines Virus Replication Abstract: Since 1998, 9 of the 26 serotypes of bluetongue virus (BTV) have ...
Proteomic characterization of murid herpesvirus 4 extracellular virions.
Virion Abstract: Gammaherpesvirinae, such as the human Epstein-Barr virus (EBV) and the Kaposi’s sarcoma associated herpesvirus (KSHV) are highly prevalent pathogens that have been associated with several ...