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Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.

individuals, especially those with human immunodeficiency virus (HIV) coinfection. The adaptive immune response mediated by CD4 + and CD8 + T cells is known to confer protection against TB. Hence, vaccines ...

A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.

Replicase RNA, Viral Triazines Tumor Cells, Cultured Virus Replication Abstract: We report on the highly potent and selective antipestivirus activity of 5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo ...

Development of bovine herpesvirus 4 as an expression vector using bacterial artificial chromosome cloning35

SB- IM Sites study technology Universities university use Vector veterinary Veterinary Medicine VIRUS Virus Replication Abstract: Several features make bovine herpesvirus 4 (BoHV-4) attractive as ...

Reduced proviral loads during primo-infection of sheep by Bovine Leukemia virus attenuated mutants.

propose a model of opportunistic replication of the virus supported by a general activation process of B lymphocytes. Health Topics:  Animal health Category:  A1 FOS Classification:  4.03 Veterinary science ...

Long-term protection against bovine leukaemia virus replication in cattle and sheep.

Issue Pt 4, p.957-63 (2000) Keywords: Animals Cattle Enzootic Bovine Leukosis Leukemia Virus, Bovine Sheep Time Factors Vaccines, Attenuated Viral Vaccines Virus Replication Abstract: In this report, we ...

Acute pancreatitis in chickens due to non-virulent Newcastle disease virus.

from a backyard flock. Using monoclonal antibodies, the virus was shown to be different from the vaccinal virus strains Hitchner, La Sota and Ulster. The virus was shown to replicate in the pancreas of ...

Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames.

Viral Sequence Deletion Sheep Trans-Activators Transcriptional Activation Viral Vaccines Virus Replication Abstract: Complex oncoviruses contain, in addition to the classical retroviral genes (gag, pol, ...

A case of convergent evolution: Several viral and bacterial pathogens hijack RSK kinases through a common linear motif.

Mitogen-Activated Protein Kinase Kinases Ribosomal Protein S6 Kinases, 90-kDa Virus Diseases Virus Replication Viruses Abstract: Microbes have been coevolving with their host for millions of years, exploiting host ...

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