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Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.

picornaviral polyprotein is essential for viral replication. Therefore, viral proteases are attractive targets for anti-viral therapy. Most assays available for testing proteolytical activity of proteases are ...

The impact of viral tropism and housing conditions on the transmission of three H5/H7 low pathogenic avian influenza viruses in chickens.

level of influence depends on the virus under consideration and, more specifically, its principal replication sites. Health Topics:  Cabine de bronzage Category:  A1 FOS Classification:  3.02 Clinical ...

Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep.

Outbreaks Europe Female Reassortant Viruses RNA, Viral Serotyping Sheep, Domestic Vaccines, Subunit Viral Vaccines Virus Replication Abstract: Since 1998, 9 of the 26 serotypes of bluetongue virus (BTV) have ...

Proteomic characterization of murid herpesvirus 4 extracellular virions.

Virion Abstract: Gammaherpesvirinae, such as the human Epstein-Barr virus (EBV) and the Kaposi’s sarcoma associated herpesvirus (KSHV) are highly prevalent pathogens that have been associated with several ...

An essential role for γ-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle.

CD8-Positive T-Lymphocytes Gammaherpesvirinae Gene Expression Regulation, Viral Genome, Viral Lymphoproliferative Disorders Malignant Catarrh Plasmids Rabbits Virus Latency Virus Replication Abstract: ...

Different replication profiles in specific-pathogen-free chickens of two H7 low pathogenic avian influenza viruses isolated from wild birds.

Pathogen-Free Organisms Time Factors Virus Replication Abstract: During an active wild bird survey conducted in Belgium from 2007 to 2011, two low pathogenic avian influenza (LPAI) H7 viruses were isolated from ...

Impact of a novel inactivated PRRS virus vaccine on virus replication and virus-induced pathology in fetal implantation sites and fetuses upon challenge.

reproductive syndrome virus Pregnancy Pregnancy Complications, Infectious Sus scrofa Swine Vaccination Vaccines, Inactivated Viral Vaccines Viremia Abstract: Preventing congenital infection is important for the ...

Antibody evasion by a gammaherpesvirus O-glycan shield.

Sequence Alignment Viral Envelope Proteins Virion Virus Replication Abstract: All gammaherpesviruses encode a major glycoprotein homologous to the Epstein-Barr virus gp350. These glycoproteins are often ...

Overlapping signals for translational regulation and packaging of influenza A virus segment 2.

and replicated poorly, producing virions with elevated particle: PFU ratios. Analysis of the genome content of virus particles showed reduced packaging of the mutant segment 2 vRNAs. Overall, we ...

Capsid proteins from field strains of foot-and-mouth disease virus confer a pathogenic phenotype in cattle on an attenuated, cell-culture-adapted virus

Volume 92, Issue 5, Number 1151 (2011) Abstract: Chimeric foot-and-mouth disease viruses (FMDV s) have been generated from plasmids containing full-length FMDV cDNAs and characterized. The parental virus ...

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