Résultats de la recherche - 102 results

A Multifaceted Approach for Evaluating Hepatitis E Virus Infectivity In Vitro: Cell Culture and Innovative Molecular Methods for Integrity Assessment

Publication Type: Peer reviewed scientific article Authors: Tatjana Locus; Lambrecht, Ellen; Sophie Lamoral; Willems, Sjarlotte; Steven Van Gucht; Vanwolleghem, Thomas; Michael Peeters Source: Veterinary Sciences, Volume 10, Issue 12 (2023) Health Topics: ...

RE-Place: A Unique Project Collecting Expertise on New Approach Methodologies

computer modeling, high throughput testing, omics, and sophisticated cell cultures, the use of experimental animals in the life sciences can be reduced or sometimes even completely avoided. Stimulating NAM ...

Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production

Publication Type: Peer reviewed scientific article Authors: Antoine Francotte; Raphael Esson; Eric Abachin; Melissa Vanhamme; Alexandre Dobly; Bruce Carpick; Sylvie Uhlrich; Jean-François Dierick; Celine Vanhee Source: Talanta, Volume 236 (2022) Health To ...

A Role for B Cells to Transmit Hepatitis C Virus Infection.

patients. Our knowledge on the infectivity of clinical HCV strains is hampered by the lack of cell culture systems that support efficient viral replication. We and others have reported that HCV can associate ...

Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation through a TLR2/MyD88 Pathway.

Biol, Volume 64, Issue 1 (2021) Keywords: Animals Aspergillosis Aspergillus fumigatus Asthma Cells, Cultured Cladosporium Cytokines Dendritic Cells Disease Models, Animal Eosinophils Inflammation Lectins, ...

Piacentinu Ennese PDO cheese as reservoir of promising probiotic bacteria.

area of Enna (Sicily, Italy), using raw ewe’s milk without the addition of any starter cultures. In the present study, the  Lactobacillus  population of Piacentinu Ennese PDO cheese was in vitro screened ...

Isoniazid Bactericidal Activity Involves Electron Transport Chain Perturbation.

potential. Importantly, inhibition of cytochrome oxidase significantly reduced cell recovery during INH challenge in a culture settling model, suggesting that the respiratory reprogramming to the cytochrome ...

Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.

H9N2 clones, selected on different cell types, named MDCK-and CEF-clone in regards to the cell culture used, were studied in vivo, revealing two different virulence phenotypes. Subsequently, the ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...

Pre-exposure intradermal rabies vaccination: a non-inferiority trial in healthy adults on shortening the vaccination schedule from 28 to 7 days.

(two doses of 0.1 ml ID of the human diploid cell culture rabies vaccine (HDCV) at day 0 and 7) versus a standard three-visit schedule (single dose of 0.1 mL ID at day 0, 7, and 28). One to three years ...

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