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Résultats de la recherche - 6 results

Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.

substances could all be assigned to one of the four priority classes (ranging from low to very high concern). Importantly, 19 substances were considered of very high concern due to in vivo genotoxicity. Five ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

With an accuracy of 100%, when equivocal results were considered positive, the results showed that combining HepaRG ™ cells with a genotoxin-specific qPCR array can improve (geno)toxicological hazard ...

Coatings in food contact materials: Potential source of genotoxic contaminants?

context and from the European CH emicals Agency (ECHA) website. In total, 53 substances were identified as genotoxic in both in silico models, of which ten were considered to be of high concern. For most of ...

Printed paper and board food contact materials as a potential source of food contamination.

(77%) considered non-evaluated in terms of potential toxicity. Based on a preliminary study of their physicochemical properties, it is estimated that most of the non-evaluated single substances have the ...

Evaluation of the potential health risks of substances migrating from polycarbonate replacement baby bottles.

the study, four baby bottles were considered of high concern because of the potential toxicity of migrating compounds. Health Topics:  Food contact materials Bisphenol A Food consumption and food safety ...

Study of the possible migration risks of food contact materials for children under 3 years

be identified. Given the lack of information for the other FCM s categories than baby bottles, and considering the major importance of the latter for infant feeding, the migration tests were started on ...

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