Résultats de la recherche - 6 results

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

set of 5845 Illumina sequences. To give estimates of error rates, we use a prospectively collected dataset of 4362. Using culture based DST as the reference, we estimate to be 100%, 95%, 82%, 99% ...

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

Mathys Source: Euro Surveill, Volume 24, Issue 11 (2019) Abstract: IntroductionIn 2007, a new federal legislation in Belgium prohibited non-biosafety level 3 laboratories to process culture tubes suspected ...

MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles

cultures. In total 88.6% (172/194) of the samples were correctly identified on the species-level using a cut-off score of 1.8 and 91.75% (178/194) using a cut-off of 1.65. All samples of the Mycobacterium ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

linezolid, moxifloxacin and bedaquilin), twice the critical concentration was added to the cultures of two pansensitive M. tuberculosis strains. Samples were taken 0h, 2h, 6h and 24h after the administration ...

Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs

the critical concentration was added to the cultures of two pansensitive M. tuberculosis strains. Samples were taken 0h, 2h, 6h and 24h after the administration of the drug.  RNA was extracted combining ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

in resistant, microbes within a few hours. This has the advantage that long culture-dependent steps are avoided, yet the resistance phenotype is detected independent of the specific cause ...

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