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Résultats de la recherche - 116 results

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells

were developed based on an extended reference dataset of 38 chemicals including existing as well as newly generated gene expression data. Both unsupervised and supervised machine learning algorithms were ...

Listeria monocytogenes isolates from Cornu aspersum snails: Whole genome-based characterization and host-pathogen interactions in a snail infection model.

strongly associated with cases of human infection. All isolates contained intact genes associated with invasion and infection while hypervirulent isolates are adapted to host environment, possessing genes ...

Staphylococcal enterotoxin gene cluster: prediction of enterotoxin (SEG and SEI) production and of the source of food poisoning based on Saβ typing.

using commercially available kits.Six genes (and), encoding putative and undetectable enterotoxins, are located on the enterotoxin gene cluster () which is part of the genomic island Saβ. These ...

Efficient control of Japanese encephalitis virus in the central nervous system of infected pigs occurs in the absence of a pronounced inflammatory immune response.

where JEV replication was not completely controlled by this mechanism, a short but strong induction of chemokine gene expression was detected. An increased IFN y expression was simultaneously observed, ...

Assessing the endocrine activity of PAHs using the DRE-, ERE- and PPARγ CALUX bioassays

was to determine the endocrine activity of 9 PAH s using three different CALUX bioassays: DRE- CALUX, ERE- CALUX and PPAR γ CALUX. Materials and methods Three CALUX (chemically activated luciferase gene ...

Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.

Volume 50, Issue 1 (2019) Keywords: Animals Chickens Gene Expression Regulation Genome, Viral Hemagglutination Inhibition Tests Immunity, Innate In Vitro Techniques Influenza A Virus, H9N2 Subtype ...

Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.

NF-κB signaling and a cysteine protease that cleaves substrates, leading to the expression of immunoregulatory genes. Here, we examined the impact of genetic or pharmacological MALT1 inhibition in mice on ...

Clonal Spread of Candida glabrata Bloodstream Isolates and Fluconazole Resistance Affected by Prolonged Exposure: a 12-Year Single-Center Study in Belgium.

8 (2018) Keywords: antifungal resistance Candida glabrata Gene Expression genotypic identification Abstract: is a major cause of candidemia in immunocompromised patients and is characterized by a high-level ...

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