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Résultats de la recherche - 31 results

Engineering nucleases for gene targeting: safety and regulatory considerations.

(2014) Keywords: Deoxyribonucleases Gene Targeting Genetic Therapy Humans SAFETY Abstract: Nuclease-based gene targeting (NBGT) represents a significant breakthrough in targeted genome editing since it is ...

Assessment of pfcrt 72-76 haplotypes eight years after chloroquine withdrawal in Kinshasa, Democratic Republic of Congo.

Resistance Female Gene Frequency Haplotypes Humans Infant Infant, Newborn Malaria, Falciparum Male Membrane Transport Proteins Mutant Proteins Plasmodium falciparum Protozoan Proteins Real-Time Polymerase ...

Biosafety of Gene Therapy Vectors Derived From Herpes Simplex Virus Type 14581

Publication Type: Peer reviewed scientific article Authors: Lim,F.; Khalique,H.; Ventosa,M.; Aline Baldo Source: Current Gene Therapy, Volume 13, Issue 6, Number 491, p.478- 491 (2013) ISBN: ...

Biosafety of viral vectors commonly used in gene therapy and vaccination.

Publication Type: Peer reviewed scientific article Authors: Philippe Herman Source: Curr Gene Ther, Volume 13, Issue 6, p.383-4 (2013) Keywords: Genetic Therapy Genetic Vectors Hazardous Substances ...

Environmental risk assessment of clinical trials involving modified vaccinia virus Ankara (MVA)-based vectors.

strain, which has been developed as a vaccine against smallpox, is since the nineties widely tested in clinical trials as recombinant vector for vaccination or gene therapy applications. Although MVA is ...

General considerations on the biosafety of virus-derived vectors used in gene therapy and vaccination.

introductory paper gathers general considerations on the biosafety of virus-derived vectors that are used in human gene therapy and/or vaccination. The importance to assess the potential risks for human health ...

Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.

lead to the emergence/selection of resistant variants hampering further treatment. Therefore, it was the purpose of this study to investigate the intra-host variation of the RdRp gene, targeted by ...

Biosafety aspects of modified vaccinia virus Ankara (MVA)-based vectors used for gene therapy or vaccination.

Clinical Trials as Topic Gene Transfer Techniques Genetic Therapy Genetic Vectors Humans Mammals Neoplasms Poxviridae Infections Practice Guidelines as Topic Vaccination vaccinia virus Viral Vaccines ...

Microbiological and molecular assessment of bacteriophage ISP for the control of Staphylococcus aureus

Hermans,K.; Lavigne,R. Source: PLoS One, Volume 6, Issue 9, p.e24418 (2011) Keywords: Antibiotic resistance phage phage therapy Staphylococcus aureus Abstract: The increasing antibiotic resistance in bacterial ...

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