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Résultats de la recherche - 111 results
Shifting national surveillance of Shigella infections toward geno-serotyping by the development of a tailored Luminex assay and NGS workflow.
a Shigella-specific deletion in the spermidine acetyltransferase gene speG, reflecting its metabolic decay. For Shigella serotype prediction, the multiplex assay scored a sensitivity and specificity of 96.6% and 98.4%, ...
Study of the underlying mechanisms and consequences of pathogenicity differences between two in vitro selected G1-H9N2 clones originating from a single isolate.
Volume 50, Issue 1 (2019) Keywords: Animals Chickens Gene Expression Regulation Genome, Viral Hemagglutination Inhibition Tests Immunity, Innate In Vitro Techniques Influenza A Virus, H9N2 Subtype ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid
anti-tuberculous drug from the same class. Although delamanid is found to inhibit cell wall synthesis, the expression of genes involved in this process were only mildly affected. In contrast, a clear parallel was ...
Relation between broiler and human Campylobacter jejuni strains isolated in Belgium from 2011 to 2013.
evaluation of the relation was based on the characteristics determined using multilocus sequence typing (MLST) alone and combined with flagellin gene A restriction fragment length polymorphism (flaA- RFLP) ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
performed directly on crude cell lysate using a combination of the bead-based MagPixTM (Luminex) and QuantigeneTM Plex (Thermo Fischer) technology. Normalized, relative genes expression levels (control vs ...
Molecular epidemiology and antimicrobial resistance mechanisms of Campylobacter coli from diarrhoeal patients and broiler carcasses in Belgium.
multilocus sequence typing (MLST), porA typing, flagellin gene A restriction fragment length polymorphism (flaA- RFLP) typing, and by PCR binary typing (P- BIT). Thirty-two MLST sequence types, 24 flaA types, ...
Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing
identified across nine genes, and individual phenotypes were predicted unless mutations of unknown association were also present. To identify how whole-genome sequencing might direct first-line drug therapy, ...
Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins.
haemagglutinin-neuraminidase (HN), are key factors in mumps pathogenesis and are important targets for the immune response during mumps virus infection. We compared the predicted amino acid sequences of the F and HN genes from ...
Inhibition of MALT1 decreases neuroinflammation and pathogenicity of virulent rabies virus in mice.
NF-κB signaling and a cysteine protease that cleaves substrates, leading to the expression of immunoregulatory genes. Here, we examined the impact of genetic or pharmacological MALT1 inhibition in mice on ...
Clonal Spread of Candida glabrata Bloodstream Isolates and Fluconazole Resistance Affected by Prolonged Exposure: a 12-Year Single-Center Study in Belgium.
8 (2018) Keywords: antifungal resistance Candida glabrata Gene Expression genotypic identification Abstract: is a major cause of candidemia in immunocompromised patients and is characterized by a high-level ...