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Résultats de la recherche - 7 results
Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.
quinones altertoxin I (ATX-I), ATX- II, ATX- III, alterperylenol (ALP), and stemphyltoxin III (STTX- III) showed in vitro genotoxic and mutagenic properties. Of all identified Alternaria toxins, the ...
A Benchmark Dose-based strategy for evaluating the combined effects of genotoxic compounds
Belgium (2023) Keywords: benchmark dose modelling genotoxicity mixtures Health Topics: Food consumption and food safety Consommation et sécurité alimentaires Voedselconsumptie en –veiligheid Service: ...
Towards Characterization and genotoxicity assessment of mycotoxin mixtures present in food.
Mertens Source: BelTox Annual Meeting, Brussels, Belgium (2023) Keywords: additivity benchmark dose modelling genotoxicity mixtures Mycotoxins Health Topics: Food consumption and food safety Consommation ...
EFSA Project on the use of New Approach Methodologies (NAMs) for the hazard assessment of nanofibres. Lot 1, nanocellulose oral exposure: gastrointestinal digestion, nanofibres uptake and local effects
(i) assessment of the uptake and potential crossing of the intestinal barrier by NC, (ii) assessment of local effects, including inflammation and genotoxicity, on the gastrointestinal epithelia, and ...
The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)
Source: Joint 3R Symposium 2023 (2023) Keywords: genotoxicity NAMs transcriptomic biomarker Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des ...
An AOP-based IATA to pave the way toward animal-free genotoxicity testing
Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens Source: Joint 3R Symposium 2023, Brussels, Belgium (2023) Keywords: adverse outcome pathways genotoxicity ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
methodologies (NAM s) to identify molecular events underlying the genotoxic mode of action of chemicals. Previously, we developed the GENOMARK biomarker, consisting of 84 genes selected based on whole genomics ...