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Résultats de la recherche - 121 results

Ecotoxicity profile of heavily contaminated surface water of two rivers in Tunisia

chronic ecotoxicity was observed in all the studied organisms, however, no genotoxic activity was detected. The presence of metals and textile disperse dyes could be associated with the ecotoxicological ...

Chemical and toxciological characterization of e-liquid cigarettes

through e-cigarette use. In the final experimental part of the thesis, we focused on the identification of potential genotoxic flavouring substances in e-liquids through the use of non-animal methodologies. ...

New QSAR models to predict chromosome damaging potential based on the in vivo micronucleus test

Emilio Source: Toxicology Letters, Volume 329, Number 84 (2020) Keywords: Chromosome damage genotoxicity In silico model In vivo micronucleus QSAR Abstract: A large number of computer-based prediction ...

Risk assessment of ochratoxin A in food

tumours in rodents. OTA is genotoxic both in vitro and in vivo; however, the mechanisms of genotoxicity are unclear. Direct and indirect genotoxic and non‐genotoxic modes of action might each contribute to ...

Phytochemical screening, antioxidant, anticoagulant and in vitro toxic and genotoxic properties of aerial parts extracts of Fumaria officinalis L. growing in Tunisia

Number 273 (2020) Keywords: Comet Assay Extracts Flavonoid content Fumaria officinalis L. genotoxicity In vitro toxicity Phenolic content Vitotox test Abstract: Fumaria is an important plant species with ...

Risk assessment of aflatoxins in food

exposure. Aflatoxins are genotoxic and AFB1 can cause hepatocellular carcinomas (HCC s) in humans. The CONTAM Panel selected a benchmark dose lower confidence limit (BMDL) for a benchmark response of 10% of ...

Assessment of natural coagulants to remediate Tunisian textile wastewater by combining physicochemical, analytical, and toxicological data

investigate physicochemical properties and in vitro (geno)toxicity with analytical chemistry. Both natural coagulants could significantly improve the physicochemical properties of the textile wastewater samples ...

Increased surface area of halloysite nanotubes due to surface modification predicts lung inflammation and acute phase response after pulmonary exposure in mice

epithelial cells. Lung inflammation, acute phase response and genotoxicity were assessed 1, 3, and 28 days after a single intratracheal instillation of adult female C57BL /6 J BomTac mice. The doses were 6, 18 ...

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

effects of extremely low-frequency (electro)magnetic fields (ELF-(E) MF s) have long been investigated, but the results are still inconclusive. With respect to genotoxicity, sound data related to the ...

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