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Résultats de la recherche - 13 results

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

DNA microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for ...

Development, Validation and Application of a Targeted LC-MS Method for Quantification of Microcystins and Nodularin: Towards a Better Characterization of Drinking Water

(PPIIA), disrupting cell growth and metabolism [15,16]. When ingested, these toxins are transported by the bile salts to the liver, potentially causing liver damage [17,18,19]. Health Topics:  Food ...

Migration of mineral oil from cardboard packaging for food: Identification of the hazards and assessment of the exposure of the Belgian population

results were obtained, including further evidence that highly alkylated polycyclic aromatic hydrocarbons (PAH s) (which are important constituents of the MOAH fraction) are not metabolized into DNA ...

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

for pharmaceutical, chemical, and consumer products, as afflicted compounds have to be (prematurely) abandoned or further tested on animals. Using the metabolically competent human HepaRG ™ cell line and toxicogenomics ...

Genotoxicity studies on plant growth promoting smoke-water and smoke-derived compounds using Vicia faba and Persea americana S10 metabolic activation

Publication Type: Peer reviewed scientific article Authors: Partoens, M.; Kulkarni, M.G.; M.E. Light; J.C. Chukwujekwu; Luc Verschaeve; Van Staden, J. Source: South African Journal of Botany, Volume 115, Number 275 (2018) Health Topics:  Health and enviro ...

Cytotoxicity and genotoxicity investigations on plant growth promoting smoke-water and smoke-derived compounds using Vicia faba and Persea americana S10 metabolic activation.

Publication Type: Dissertation Authors: Partoens, M. Source: UAntwerpen and University of Kwazulu-natal, Antwerp, Belgium- Durban, South Africa, p.NA (2016) Accession Number: NA Keywords: cytotoxicity genotoxicity growth investigation Persea americana S10 ...

Systematic identification of hypothetical bacteriophage proteins targeting key protein complexes of pseudomonas aeruginosa

expressed genes of lytic bacteriophages, whose products are involved in the subversion of the host metabolism. In this study, we focused on the composition of important macromolecular complexes of Pseudomonas ...

Development of giant bacteriophage phiKZ is independent of the host transcription apparatus

Institute IS IT journal Laboratories map metabolism microbiology Molecular ON Operon Paper physiology protein Proteins Pseudomonas Pseudomonas aeruginosa Pseudomonas Phages Research Research Support Rna ...

Urinary nicotine metabolites: usefulness as biomarkers of smoking status

metabolism, with higher ratios indicating faster metabolism. Evidence shows that the ratio, in urine, saliva or plasma, could predict responses to smoking cessation medication and guide pharmacotherapy. Since ...

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