Résultats de la recherche - 9 results
The landscape of drug resistance in Plasmodium falciparum malaria in the Democratic Republic of Congo: a mapping systematic review
Source: Trop Med Health, Volume 51, Issue 1 (2023) Keywords: Antimalarial drug resistance Democratic Republic of Congo Malaria Molecular markers of drug resistance mutations Abstract: CONTEXT: The ...
Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs.
J (2020) Abstract: Conventional molecular tests for detecting complex (MTBC) drug resistance on clinical samples cover a limited set of mutations. Whole genome sequencing (WGS) typically requires culture. ...
Molecular surveillance of anti-malarial drug resistance in Democratic Republic of Congo: high variability of chloroquinoresistance and lack of amodiaquinoresistance.
Mutation Plasmodium falciparum Polymorphism, Genetic Prospective Studies Protozoan Proteins Young adult Abstract: BACKGROUND: The loss of chloroquine (CQ) effectiveness has led to its withdrawal from ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
the knowledge on resistance mutations which is limited for especially 2nd-line and new drugs, (b) do not distinguish living from death cells, (c) ignore all intrinsic resistance mechanisms like efflux ...
Genetic Basis and Clonal Population Structure of Antibiotic Resistance in Isolated From Broiler Carcasses in Belgium.
resistant isolates. Regarding resistance to erythromycin, different mutations occurred in diverse genetic loci, including mutations in the 23S rRNA gene, the and ribosomal genes, and the intergenic region ...
Comparative genomics of quinolone-resistant and susceptible Campylobacter jejuni of poultry origin from major poultry producing European countries (GENCAMP)
isolates clustered in four main clusters. All trees revealed that the isolates were clustered according to the presence/absence of the gyrA mutations causing fluoroquinolone resistance and ST-types. The ...
Falciparum malaria molecular drug resistance in the Democratic Republic of Congo: a systematic review.
Melin; Patrick De Mol; Marie-Pierre Hayette Source: Malar J, Volume 14 (2015) Keywords: Democratic Republic of the Congo Drug Resistance Humans Malaria, Falciparum Mutation Plasmodium falciparum Abstract: ...
Dissecting the molecular evolution of fluoroquinolone-resistant Shigella sonnei.
fluoroquinolone-resistant S. sonnei. We reaffirm that extant resistant organisms belong to a single clonal expansion event. Our results indicate that sequential accumulation of defining mutations (gyrA- S83L, parC- S80I, and ...
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.
Egypt before disseminating into Northern, Southern and Western Africa, then to the Middle East, Asia and the European Union. The MDR clone has since accumulated various substitution mutations in the ...