Résultats de la recherche - 103 results

Advanced Methods for Dose and Regimen Finding During Drug Development: Summary of the EMA/EFPIA Workshop on Dose Finding (London 4-5 December 2014).

and adaptive studies). Pairwise comparisons were also discussed during the workshop; however, mostly for historical reasons. This paper discusses the added value and limitations of these methods as well ...

Survey on the Use of Whole-Genome Sequencing for Infectious Diseases Surveillance: Rapid Expansion of European National Capacities, 2015-2016.

public health reference laboratories in 22 and 25 countries had access to WGS-based typing for public health applications in 2015 and 2016, respectively. Reported reasons for limited or no access were lack ...

Zona pellucida gene mRNA expression in human oocytes is related to oocyte maturity, zona inner layer retardance and fertilization competence.

response resulted in a noninvasive oocyte fertilization prediction model. LARGE SCALE DATA: Not applicable. LIMITATIONS, REASONS FOR CAUTION: This is a retrospective study and the relation of oocyte mRNA ...

Slurry photocatalytic membrane reactor technology for removal of pharmaceutical compounds from wastewater: Towards cytostatic drug elimination

than the ones observed with slurry PMR s. Therefore the reasons why slurry PMR s may be considered as the next generation technology will be discussed in this work together with the limitations related ...

Pre-registration efficacy study of a novel marker vaccine against classical swine fever on maternally derived antibody positive (MDA+) target animals.

efficacy of live attenuated vaccines against classical swine fever (CSF). For this reason, a marker vaccine candidate CP7_E2alf was tested for its efficacy in the presence of MDA. Pregnant sows were ...

Pediatric diabetes centres rated parental responsibility and family support as most important determinants of HbA1c using a 17-item questionnaire: a pilot study

for PH was present (e.g. adolescence), PDC s also scored this factor highly. — A qualitative analysis of free-text reasons for EH and PH provided information on how to improve the questionnaire for ...

Genetic damage in humans exposed to extremely low-frequency electromagnetic fields.

As a matter of fact, there are reasons to believe that effects are not that impressive. However, the totality of the studies cannot simply be disregarded warranting further caution and the application, ...

Final transitions to place of death: patients and families wishes.

settings of cancer patients and the extent to which patient/family wishes are cited as a reason for the transition. METHODS: Data were collected from the EUROSENTI- MELC study over a 2-year period. General ...

Construction of Nontoxigenic Mutants of Nonproteolytic Clostridium botulinum NCTC 11219 by Insertional Mutagenesis and Gene Replacement.

translated into guidelines for the food industry; in contrast, the effectiveness of emerging processing and preservation techniques has been poorly documented. The reason is that experimental studies with C. ...

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