Résultats de la recherche - 93 results
Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability.
assessor’s reasoning to omit a MoS calculation and to focus more on local toxicity and mutagenicity/genotoxicity for ingredients for which limited systemic exposure is to be expected. Health Topics: ...
Evaluation of detection methods for non-O157 Shiga toxin-producing Escherichia coli from food.
this pathogen is of great importance for public health reasons. In this study the detection and isolation of four non- O157 STEC strains (O26, O103, O111, O145) from different artificially contaminated ...
Analysis of illegal peptide biopharmaceuticals frequently encountered by controlling agencies.
distributions of these substances. At their request, suspected protein and peptide preparations are analysed in our Official Medicines Control Laboratory (OMCL). It stands to reason that a general screening ...
Biological activity conferred by endocrine disrupting chemicals in hospital effluent and river water from the Brussels Region, Belgium
s). For this reason, the Water Framework Directive (WFD, amended in 2013/39/ EU) established a priority list of 33 new and 8 previously regulated chemical pollutants, some of which have shown to ...
How well do physical activity questions perform? A European cognitive testing study.
intensity which would be desirable to obtain from a scientific point of view; however, respondents can hardly provide this information for cognitive reasons. Studies investigating the respondents’ perspective ...
Barriers to and facilitators of compliance with clinic-based cervical cancer screening: population-based cohort study of women aged 23-60 years.
travel costs and other direct non-medical costs incurred in attending clinic-based cervical cancer screening, (b) investigating screening compliance and reasons for noncompliance, (c) determining women’s ...
Transitions between health care settings in the final three months of life in four EU countries
Patient wishes were cited as the reason for the last transition before death in 27%, 39%, 9% and 6% of cases in Belgium, Netherlands, Italy and Spain, respectively (P < 0.001). CONCLUSION: End-of-life ...
Safety, immunogenicity, and efficacy of the candidate tuberculosis vaccine MVA85A in healthy adults infected with HIV-1: a randomised, placebo-controlled, phase 2 trial.
M tuberculosis infection or disease, although the study was underpowered to detect an effect against disease. Potential reasons for the absence of detectable efficacy in this trial include insufficient induction ...
Human biomonitoring of multiple mycotoxins in the Belgian population: Results of the BIOMYCO study.
assessment at individual level. For this reason, the BIOMYCO study was designed to assess mycotoxin exposure in Belgian adults and children using urinary biomarkers of exposure. Morning urine was gathered in ...
Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.
no longer detected in 13 of 15 treated mice. All eight untreated mice suffered from an acute generalized disease and were euthanized for ethical reasons on average at 4 dpi. These results illustrate ...